Полтавський державний медичний університет та Всеукраїнська громадська організація «Наукове товариство анатомів, гістологів, ембріологів і топографанатомів України»
MORPHOLOGICAL CHANGES IN THE LIVER OF RATS DURING CHRONIC INTOXICATION PESTICIDE OF 2,4-DA AND CORRECTION OF ANTIOXIDANTS THEIR COMPLEX
In an experiment rats pesticide of 2,4-DA was entered males in a flow 30 days, that led to the expressed general somatic indexes and histological changes liver. Introduction of complex AO an animal resulted in diminishing of pathological changes in histostructur of liver, that testifies for expedience of application of complex AO for treatment and prophylaxis of intoxication pesticide of 2,4-ДА.
PSYCHOLOGICAL STATUS OF ADOLES-CENTS WITH ACUTE PUS LYMPHADENITIS IN ANTEROPERATIONAL PERIODS
In the article based on the psychodiagnostic investigation of 36 adolescents which expecting a surgery operation due to the acute pus lymphadenitis there were studied their characterological peculiarities and anxious level. There were established that main part of patients has obvious character’s accentuation, mainly emotion’s lively and dystimic types. Levels of situation’s and person’s anxious were in the normal ranges. Based on the results of investigation main psychocorrection’s ways with the adolescents during all stages of surgery operation were made.
DIAGNOSTICS AND TREATMENT OF SPONTANEOUS PNEUMOTHORAX
For period since 2006 and 10 months of 2009 observed 148 patients with spontaneous pneumothorax. Incomplete spontaneous pneumo-thorax has 24(16,2%) sick, subtotal - 7 (47,2%), total 53(35,8%), tense 4(2,7%), rigid - 2 persons. Recurrent spontaneous pneumothorax existed beside 18(12,1%) sick. Respiratory insufficiency I degree had 104(72,2%) sick, II degree - 42(28,3%), III degree - 2(1,3%) sick. Period of stay in permanent establishment 12,6 days. The relapse of SP appeared had 6 sick. The low-invasive methods mainly used at treatment of second group sick. The reason of spontaneous pneumothorax had realized for 53(49,1%) sick. The intermediate term of stay in permanent establishment was 7,2 day.
INFLUENCE OF ACUTE BLOOD-LOOSING ON IONIC BALANCE OF A BRAIN IN AFTEROPERATION PERIOD
In clinical conditions (63 patients) are studied influence acute blood-loosing on an ionic homeostasis of a brain. The possible reasons of cerebral insufficiency and infringement of consciousness at patients of the given category are established
EFFICACY OF MACROLIDES IN THE TREATMENT OF INFECTIOUS-DEPENDENT ACUTE AND CHRONIC COPD DISEASE
Studied the effect of Rovamycin in the treatment of patients with acute infectious diseases оf the lower respiratory tract and infection-dependent exacerbation of asthma. There was normalization of body temperature and the disappearance of signs of intoxication for 2-4 days of treatment in patients treated Rovamycin. Shown that Rovamycin exhibits high efficiency, low-toxic and virtually harmless, may be the drug of choice in empirical therapy of infectious respiratory diseases.
MODERN VIEWS AT THE ROLE OF IMMUNOLOGIC APPARATUS OF PERIODONTIUM DURING THE INFLAMMATORY PROCESS, ITS CHARACTER AND FINAL CONSEQUENCES
At present time the generally accepted is the fact of infections ethyology of periodontium diseases. There was conducted the survey of modern literature on the questions of interrelations of infections agents and protective powers of organism, adaptive innate links of the immune system and formation of inflammation in periodontium. There were examined the investigations on the reason which confirm rebuilding of non-specific and specific reactivity of the organism at some forms of inflammation of periodontium and correspondingly the development of tissue reaction in periodontium. There was paid attentions on the role of microbe parodontopathogens in the development of periodontium diseases in children, the was noted the lack of information about inflammatory process in periodontium of the deciduous teeth.
immune system microbe parodontopathogens
DIDACTIC BASES OF THE TEACHING THE SURGICAL SECTION ON PREATTESTATION CYCLE OF EMERGENCY MEDICINE STATES SPECIALISTS
In the articles considered of questions of didactics bases of advanced studies and was analysed the base and perspective methods of studies of emergency medicine states specialists. On the basis of scientific analysis of educational program and academic curriculum developed suggestion to the improvement of studies process.
THE ANALYSIS OF WAYS OF INDIRECT RESTORATIONS
In the work is carried out the analysis of techniques of fixings of indirect restorationsis, was given a conclusions of interrelation of the technique of fixing and the area of indirect restoration, there were made the recommendations concerning application of this or that technique in each concrete clinical case.
FUNCTIONALLY PROVED PROSTHETICS OF TOOTHLESS JAWS
In article is offered a new tactics of prosthetics of patients with full absence of a teeth on the top and bottom jaw which at the expense of use of the shaper of planimetric curves Kubein-Messenburga, articulator Reference SL and obverse archallows could lower quantity of visits and raise the quality of treatment.
ANALYSIS OF THE RELATIONSHIP BETWEEN MORTALITY RATE AND PROVISION OF THE NEONATAL INTENSIVE CARE UNITS OF THE CHILDREN’S HOSPITALS OF UKRAINE WITH EQUIPMENT
In the article, results of the study of the relationship between mortality rate and provision of the neonatal intensive care units of the children’s hospitals of Ukraine with equipment are given. Calculation of Odds Ratios (OR) is used to assess such a relationship. A number of in-hospital factors associated with increase in mortality rate has been identified, of which the lack of CPAP-devices (OR 6,43), the total number of ventilators per 1 ICU bed being less than 1,0 (OR 5,0), the number of high-class ventilators per 1 ICU bed being less than 1,0 (OR 3,67), the number of neonatal multiparameter monitors per 1 ICU bed being less than 1,0 (OR 3,67), and the number of automated infusion pumps per 1 ICU bed being less than 1,0 (OR 2,27) are the most important.
FEATURES OF SMEAS’ CELLULAR STRUCTURE CONTENTS OF THE ORAL CAVITY FROM PER-SONS WITH TPATHOLOGY OF LOR-ORGANS
The structure of cells of smeas which are received after centrifusion of oral cavity contents from 67 persons among whom 17 - were healthy is investigated; 14 - had a chronic tonsillitis; 19 - a chronic antritis; 17 - an allergic rhinitis. Changes of structure of cells in the form of quantity reduction neutrophills and epytheliocytes, maintenance increase lymphocytes’ "naked" kernels and эритроцитов are established. Changes had an identical orientation at all investigated nosology, but differed quantitatively. Authors consider, that changes in structure of cells of oral cavity contents at patients with a lor-pathology depend on development of a system inflammation and a condition of local system of protection.
cellular structure of oral cavity contents
CHANGES OF PERIDONTAL POCKETSۥ MIKRO-FLORA IN THE PROCESS OF THE COMPLEX TREATMENT OF PATIENTS WITH GENERALIZED PERIODONTITIS IN COMBINATION
The data about quantative and quality composition of periodontal pockets microflora at patients with chronic generalized periodontitis in combination current with chronic holecystitis and pancreatitis in the process of the complex treatment were presented in this article.
HEPATOPROTECTION IN THE COMPLEX OF INTENSIVE CARE OF POSTTRAUMATIC HEPATITIS
In the investigation we performed complex clinical and laboratory examination in patients with hepatic injury on the base of different therapy strategies. We found that the time and severity of immune system reactions in traumatic disease depend on the efficacy of antitoxic therapy and complications. We showed that pathogenic treatment of such patients should include antitoxic drugs.
APPLICATION OF NOT STEROID ANTI-INFLAMMATORY PREPARATIONS AT TREATMENT OF DIABETIC ARTHROPATHY
Studied the efficacy and tolerability of NSAIDs Diklobryu in 30 patients with diabetes mellitus complicated arthropathy. Found that therapy Diklobryu positive impact on the course of diabetic arthropathy (the intensity of pain, number of inflamed joints, increases range of motion, reduces the amount of inflamed joints), reduces the level of proinflammatory cytokines. In addition, the combined use of injectable forms of tablets and the achievement of effect is achieved in much shorter time, thereby reducing the duration of NSAID receiving tablets.
CELLULAR AND HUMORAL IMMUNITY INDEXES OF PATIENTS WITH VEGETOSENSORIC POLYNEUROPATHIA DURING VIBRATIONAL DISEASE
The patients with vegetosensoric polyneuropathia during vibrational disease of II degree is reveal decrease in blood serum contents of T-lymphocytes, T-helpers, T-suppressors, B-lymphocytes, immunoglobulin’s a, M nag G. The given alterations signify the reduction of immunologic reactivity of the organism and dictate the necessity of performing an immunocorrectional and immunomodulating therapy. The patients with vegetosensoric polyneuropathia during vibrational disease of I degree do not display any alterations in lymphocytes and immunoglobulin contents.
INDICATIONS TO PRESERVATION SUITABLE FOR PROSTHETICS SINGLE STANDING ROOTS AND A TEETH
Single teeth and roots state in 37 both-sexed patients from 55 till 70 years has been analyzed in the article. There has been determined the possibility of their usage as the fixation elements in the non-fixed covering dentures as a result of clinical-rhentgenological investigations. As our observations have demonstrated, 60,7% of examined teeth and roots were suitable for the further denturing and could provide the additional fixation and stabilization of the constructions.
ORAL CAVITY’S ONCOLOGY MORBIDITY IN POLTAVA REGION
Oral cavity’s oncology morbidity in Poltava region for 5 years, from 2004 till 2008 is represented in the work. Tumors high neglect of this localization which amounts 45,3 % is being discovered. According to statistics high death PUR tfW 1 year from time of diagnosis determining amounts 29,2 % and very high rate of refuses from treatment at all stages of treatment. The summaries were done concerning late diagnosis causes of this localization.
THE ROLE OF MELATONIN AND GATRIN IN FORMING OF SECRETORY- EVACUATION DISORDERS AT GASTROESOPHAGEAL REFLUX DISEASE TAKING INTO ACCOUNT PSYCHOSOMATIC STATUS AT STUDENTS Oparin A., Oparin A., Shapovalova O.
The features of the state of motorno-evakuatornoy and secretory function are in-process studied at students at gastroesophageal reflux disease, rotined and exposed role of melatonin and gastrin in these processes, and similarly participation in them of psychosomatic disorders which at excitable patients, promoting the factor of aggression of gastric juice, and at brakes patients, reducing motorno-evaсuatіoп disorders, result in a disbalance between the factors of defence and aggression of mucous membrane, and create terms for development of GERD.
APPLICATION OF PREPARATION “СRYOСELL - THE CRYO-EXTRACT OF THE PLACENTA” IN THE COMPLEX TREATMENT OF THE AGGRAVATION OF GOUTY ARTHRITIS
Questions of the study of the biological fetoplacental tissues, which use in the cellular therapy and their pathogenetic role in the correction of basic is sectional the gouts of steel by basis for conducting of this investigation. The complex treatment of the aggravation of gouty arthritis with the application of preparation “Сroycell - the cryo-extract of the placenta” leads to the more dynamic decrease of the level of uric acid, ensures a substantial improvement in the functional activity of joints, improves the quality of the life of the patients with gout.
«Сroycell - the cryo-extract of the placenta».
SPECIAL METHODS OF THE RESEARCH AT ORTHOPEDIC TREATMENT OF PARTIAL LOSS OF THE TEETH COMPLICATED WITH PERIODONTITIS
Normalization of the occlusive and power interrelations of the teeth lines, immobilization of the stored teeth maintains the actual problems of the orthopedic treatment of the periodontitis, complication with the partial loss of the teeth. Difference in the periodontal status and clinical situation of the mouth cavity of the examined patients demand the special approach during the construction of the arch prosthesis, the necessity of the conduction of the special methods of the research. Elective grounding of the teeth on the basis of the occlusiograms, the metering of the pliability of the mucous tunic of the prosthesis box is the necessary important attribute on the levels of the preparation and handling over the clasp constructions, creating on the basis of the mathematical calculations and their elements.
MORFOLOGICAL STATE OF RETINA OF RATS DURING HYPODERMIC TRANSPLANTATION OF СRYOPRESERVED PLACENTA ON ASEPTIC RETINITIS
Research was conducted on 60 rats-males of line of «Vistar», 55 which modeled aseptic retinitis by a 5 mg of λ-каrаginanum in 1 ml of solution of NaCl, hypodermic transplantation of cryopreserved placenta was conducted,10 rats is a control group. Studied the morphological changes of retina of eyes on the early lines of experiment. It is set that modulated aseptic retinitis has the clear stages of inflamation (altiration, exudation and prolifiration). Changes arose up gradually since a ganglionary layer.
ACTIVITY OF ANTIOXIDATIC SYSTEM AT SICK OF THE PSORIASIS
It is proved, that psoriasis illness is accompanied by essential change of activity of systems antiradical and antiperoxydation protection that proves to be true depression of activity of a catalase of blood, glytationperoxydase of erythro-cytes, maintenances updated of glytation and sulfhydryl groups of blood against activity rising superoxydismutase of erythrocytes and a blood serum hepatocuprein. The most expressed changes of indicators were at average and serious degree of disease and in combination with hypertensia.
MORPHOMETRIC ESTIMATION OF RAT HEART STROMA STATE IN CONDITIONS OF SUBACUTE EFFECT OF SYDNOCARB AND IN ITS COMBINATION WITH NEUROLEPTICS
The quantitative assessment of myocardial stroma state determined an essential dependence of the intensity of interstitial tissue edema from the localization of the process under the subacute effect of sydnocarb and in conditions of its correction with neuroleptics. The experimental myocardium injury of hypoxic type, observed when sydnocarb is introduced, is detected to a greater extent in right atrium and left ventricle. Protective effect of droperidol and haloperidol regarding the development of interstitial and perivascular edema is evident during the first week of sydnocarb effect, but disappears in 14 days. The protective effect of aminazine and sulpiride is evident as from the 7th day of the subacute effect of sydnocarb. Sydnocarb introduction during two weeks doesn’t cause considerable injury of the myocardium of left atrium and right ventricle.
THE STEREOMORPHOLOGICAL FEATURES PROMOTING PROMOTION AND ALLOCATION OF THE SECRET ON EXCRETORY DUCTS OF HUMAN MINOR SALIVARY GLANDS
The purpose of our research became studying specific features of the stereomorphological device of system excretory ducts palatine and labial salivary glands on which there is a movement and allocation secretory liquids. On a course excretory ducts investigated salivary glands constantly there are sites of the retention (ampulliform expansions and narrowings) which are not an attribute of pathological dilatation, and are considered as a variant of norm.
MIGRATION AND ADHESION CHARACTERISTIC OF CELLS OF CONDUCTIVE SYSTEM IN HUMAN HEART
Migration and adhesion properties structure parts of the conductive system were investigated in the human heart from 4 to 12 week of development. Multipotential muscle cells form the nodes of the conductive system, therefore adhesion processes are predominate there. Atria-ventricular bundle form of the migratory cells, which grow up towards the top of the heart. Purkinje fibers form of migratory cells towards the ventricle wall, they have high migration potential during 9-12 weeks.
INFLUENCE OF MICROMERCURYALISM AND PROTECTING PREPARATIONS ON THE WHITE RATS SPLEEN STRUCTURE
Influence of micromercuryalism on the white rats spleen structure before and after application of protecting preparations „Thiotriazolinum” and „Mildronatum” was investigated. It was shown that the combined application of these preparations normalized ultrastructural organization of white and red pulp lymphocytes, reticuloepitheliocytes, endotheliocytes and fibrous structures.
INFLUENCE OF THE STRESS ON THE PROOXIDANT-ANTIOXIDANT SISTEM OF THE STOMACH OF THE RATS AND THEIR CORRECTION OF MELATONIN
Immobilization stress led to a decrease in activity of antioxidant enzymes of the stomach and a slight increase of pH of gastric juice. As a result, there were pronounced manifestations of stress ulcerogenic effect, as in the stomach homogenate increased level of peroxidation in the lower activity of catalase and SOD. Gastric ulcers were lower with increase introduction of melatonin (hyperme-latoninemiya), than in all other groups.
MORPHOLOGICAL AND MORPHOMETRICAL CHANGES IN RATS’ TESTICLES UNDER LONG-TERM ACTION OF USED MOTOR OIL
In the experiment on 25 white male rats there have been found the introduction of the used motor oil (UMO, 500 mg / kg) for 90 days results in significant morphofunctional disorders in the testis. On 30th day of the experiment there has been detected the thickening of the testis’ interstitium, reducing in the diameter of the convoluted seminiferous tubules, microcirculatory disorders, and suppression of the spermatids’ differentiation. On the 60th – 90th days of the experiment there have been found progressive disturbances in spermatogenesis, decomposition, disorientation, and in consequence desquamation of the spermatogenic epithelia.
CEREBELLAR PURKINJE CELLS AND THEIR RELATION WITH CAPILLARIES IN YOUNG AGE
Average number of capillaries 0,8 per one Purkinje Cells, average length – 100 mcm per cell, specific length 346 mm per cubic mm. Every Purkinje Cells has from 1 till 4 capillaries. Capillaries may lie both in ganglionic (75%), granular (16%) and molecular (9%) layers. Diffusion distance tends to be small – 25% capillaries lie less than 4 mcm to neuron body.
EXPERIMENTAL AUTOIMMUNE DISEASES OF THYROID GLAND AS ESTIMATION FIELD OF THERAPEUTIC POTENTIAL OF CRYOPRESERVED PRODUCTS OF FETOPLACENTAL COMPLEX
Basing on the experimental model of autoimmune thyroiditis the therapeutic efficiency of the introduction of native and cryopreserved fetal liver cells into animal organism is shown in this research. The advantages and possible mechanisms of therapeutic effect of preparations of embryo fetoplacental complex are discussed.