MODERN  VIEWS AT THE ROLE OF IMMUNOLOGIC APPARATUS OF PERIODONTIUM DURING THE INFLAMMATORY PROCESS, ITS CHARACTER AND FINAL CONSEQUENCES

Sheshukova O.V.; Shinkevich V.; Kaydashev I.P.

Article

World of Medicine and Biology / №1(24), 2010 / MODERN VIEWS AT THE ROLE OF IMMUNOLOGIC APPARATUS OF PERIODONTIUM DURING THE INFLAMMATORY PROCESS, ITS CHARACTER AND FINAL CONSEQUENCES

Sheshukova O.V., Shinkevich V., Kaydashev I.P.

MODERN VIEWS AT THE ROLE OF IMMUNOLOGIC APPARATUS OF PERIODONTIUM DURING THE INFLAMMATORY PROCESS, ITS CHARACTER AND FINAL CONSEQUENCES

About the author:	Sheshukova O.V., Shinkevich V., Kaydashev I.P.
Heading	LITERATURE REVIEWS
Type of article	Обзорная статья
Annotation	At present time the generally accepted is the fact of infections ethyology of periodontium diseases. There was conducted the survey of modern literature on the questions of interrelations of infections agents and protective powers of organism, adaptive innate links of the immune system and formation of inflammation in periodontium. There were examined the investigations on the reason which confirm rebuilding of non-specific and specific reactivity of the organism at some forms of inflammation of periodontium and correspondingly the development of tissue reaction in periodontium. There was paid attentions on the role of microbe parodontopathogens in the development of periodontium diseases in children, the was noted the lack of information about inflammatory process in periodontium of the deciduous teeth.
Tags	inflammation in periodontium, immune system microbe parodontopathogens, deciduous teeth.
Bibliography	Авдоніна Л.І. Перідонтит як одне з джерел ендогенної інтоксикації організму / Л.І. Авдонініа, В.В. Казакова, Н.С. Лукоянова, Ю.В. Пальона // Медичні перспективи.-2003.-Т.VIII.-№3.-С.29-31. Жеро Н.І. Імуногістохімічні методи в дослідженні деструктивных форм перідонтиту /Жеро Н.І., Лизогубов В.В., Усенко B.C. // Медичні перспективи.-2003.-T.VII, №3.-С.79-85. Канеко Т. Дендритные клетки в периапикальных тканях воспалительных повреждений. Иммуноэлектронный микроскопический анализ / Т. Канеко, X. Суда, М. Тагаки и др. // Российский стоматологический журнал.-2003.-№2.-С.7-9. Напольников Л.В. Компьютерная морфометрия маркеров азурофильной зернистости нейтрофилов крови у пациентов с острым апикальным периодонтитом / Л.В.Напольников, А.А.Славинский, Т.В.Аксенова и др.//Современная стоматология -2005. -N°2.-C. 65-61. Парпалей Е.А. Современные подходы к эндодонтическому лечению временных зубов/ Парпалей Е.А. //Дентальные технологии.- 2003.- №2 (11).-С.10-13 Терехова Т.Н. Периодонтит у детей. Часть 1: Клиника / Терехова Т.Н., Кармалькова Е.А., Козловская Л.В. // Современная стоматология.-2005.-№2.-С.20. Царев В.Н. Диагностика хронического периодонтита с помощью полимеразной цепной реакции и перспективы эндодонтического применения макролидов и цефалоспоринов / В.Н. Царев, А.В. Митронин, Ю.М. Максимовский и др. // Стоматология для всех.-2004.-№ 1.-С.8-11. Царев В.Н. Этиопатогенетические факторы развития воспалительных заболеваний периодонта / В.Н. Царев, Р.В. Ушаков, Е.Я. Ясникова и др. // Стоматолог.-2005.-№6.-С.16-23. Царев В.Н. Клинико-микробиологическое обоснование применения ксилитсодержащего реминерализующего геля для лечения кариеса зубов у детей раннего возраста /В.Н.Царёв, Е.В.Кириллова, Л.П.Кисельникова, Е.Н. Николаева //Клиническая стоматология.- 2009.-№3.- С.4-8 Activation of T cells recognizing self 60-kDa heat shock protein can protect against experimental arthritis / S.M. Anderton, R. van der Zee, B. Prakken et al. // J.Clin.Exp.Med.-1995.-Vol.l81-P.943-952. Arakawa S. Novel apoptosis-inducing activity in Bacteroides forsythus: a comparative study with three serotypes of Actinobacillus actinomycetemcomitans / S. Arakawa, T. Nakajima, H. Ishikura et al. // Infection and Immunity.-2000.-Vol.68, N8.-P.4611-4615. Baumgartner J. Experimentally induced infection by oral anaerobic microorganisms in a mouse model/ Baumgartner J., Falkler W., Beckerman T. // Oral Mocrobiol. Immunol.-1992.-Vol.7.-P.253-256. Budu С. Е. Virulence factors of Porphyromonas Gingivalis are modified by polyphenol oxidase and asparaginase / С. Е. Budu, J. Luengpailin, G. Reyes et al. // Oral Microbiol. Immunol.-2003.-Vol.l8.-P.313-317. Chen Z. Protease-active extracellular protein preparation from endodontopathogenic bacteria in human epithelial cells / Chen Z. // J.PeriodontoI.-2000.-Vol.70, N1.-P.411-435. Chen Z.Protease-active extracellular protein preparation from Porphyromonas gingivalis W83 induce N-Cadherin proteolysis, loss of cell ahgesion, and apoptosis in human epithelial cells /Chen Z., Casiano C.A., Fletcher H.M. // J.PeriodontoI.-2001.-Vol.72, N5.-P.641-650. Elias D. Induction of diabetes in standard mice by immunization with the p277 peptide of a 60-kDa heat shock protein / D. Elias, H. Marcus, T.Reshef et al. // Eur.J.Immunol.-1995.-Vol.25.-P.2851-2857. Grossi S.G., Periodontal disease and diabetes mellitus: a two-way relationship / Grossi S.G., Genco RJ. //Ann.Periodontol.-1998.-Vol.3, N 1.-P.51-61. Hafstrom C.A. Effect of treatment on some periodontopathogens and their antibody levels in periodontal abscesses / C.A. Hafstrom, M.B. Wikstrom, S.N. Renvert // J. Periodontol.-1994.-Vol.65.-P. 1022-1028. Heide S. Rolling I. Endodontic therapy in primary and young permanent teeth. / Heide S. //Finn. Dent J. - 1998. - №3.- p.170-171. Hughes C. V. Cloning and expression of a-D-glucosidase and N-acetyl-\|3-glucosaminidase from the periodontal pathogen, Tannerella forsythensis (Bacteroides forsythus) / C. V. Hughes, G. Malki.- C. Y. Loo et al. // Oral Microbiology Immunology.-2003.-Vol.l8.-P.309-312. Imberti L. Selective depletion in HIV infection of T cells that bear specific T cell receptor Vp sequences / L. Imberti, A. Sottini, A. Bettinardi et al. // Science.-1991.-Vol. 254.-P.860-862. Jiang Y. An optimal host response to a bacterium may require the interaction of leucocytes and resident host cells /Jiang Y., Schilder H. // J.Endod.-2002.-Vol.28, N4.-P.279-282. Jotwani R. Fimbriated Porphyromonas gingivalis is more efficient then fimbria-deficient P. gingivalis in entering human dendritic cells in vitro an iflamatory Thl effector response /Jotwani R., Cutler C.W. // Infect. And Immunity.-2004.-Vol.72, N3.-P.1725-1732. Kurita-Ochiai Т. Immunosuppressive factor from Actinobacillus actinomycetemcomitans down regulates cytokine production / Kurita-Ochiai Т., Ochiai K. // Infect.Immun.-1996.-Vol.64.-P.50-54. Levesque C. Coaggregation of Streptococcus salivarius with periodontopathogens: evidence for involvement of fimbriae in the interaction with Prevotella intermedia / Levesque C., Lamothe J., Frenette M. // Oral.Microbiol.Immunol.-2003.-Vol. 18, N 5.-P.333-337. Loesche W.J. Plasma lipid and blood glucose levels in patients with destructive periodontal disease / W. Loesche, F. Karapetow, A. Fohl et al. // J.Clin.Periodontol.-2000.-Vol.27,N8.-P.537-541. Martin F.E. Quantitative microbiological study of human carious dentine by culture end realtime PCR: association of anaerobes with histopathological changes in chronic pulpitis / F.E. Martin, M.A. Nadkarni, N.A. Jacques, N. Hunter // J.Clin. Microbiol.-2002.-Vol.40,No 5.-P. 1698-1704. Meyer M.W. Streptococcus sanguis-induceB platelet clotting in rabbits and hemodinamic and cardiopulmonary consequences / Meyer M.W. Gong K., Herzberg M.C. // Infect.Immun.-1998.-Vol.66, N12.-P.5906-5914. Okuda K. Purification and properties of hemagglutinin from culture supernatant of Bacteroides gingivalis / Okuda K. // Infect. Immun.-1986.-Vol.54.-P.659-665. Preshaw P.M. Porphyromonas gingivalis lipopolysaccharide delays human polymorphonuclear leukocyte apoptosis in vitro / Preshaw P.M., Schifferle R.E., Walters J.D. // J.Periodont.Res.-1999.-Vol.34.-P.197-202. Potempa J. Role of bacterial proteinases in matrix destruction and modulation of host responses / Potempa J., Banbula A., Travis J. // J.Periodontol.-2000.-Vol.24.-P.153-192. Rajapakse P.S. Immunisation vith the Rgp A-Kgp proteinase-adhesin complexes of Porphyromonas gingivalisprotects against periodontal bone loss in the rat periodontitis model / Rajapakse P.S. // Infect. Immun.-2002.-Vol.70.-P.2480-2486. Rosendahl R. Эндодонтическое лечение молочних зубов. Обзор / Rosendahl R. //Квинтэссенция-2000.-No.2.-pp.49-62. Rupf S. Comparison of profiles of key periodontal pathogens in periodontium and endodontium / S. Rupf, S. Kannengiesser, K. Merte et al. // Endod.Dent.Traumatol.-2000.-Vol.l6.- N6.-P.269-275 Sakamoto M. Rapid detection and quantification of five periodontopathic bacteria by real-time PCR / M. Sakamoto, Y. Takeuchi, M. Umeda et al. // Microbiol.Immunol.-2001-Vol.45.- Nl.-P.39-44. Sakamoto M. Reclassificafion of Bacteroides forsythus as Tannerella forsythensis corrig., gen. Nov., comb. Nov. / M. Sakamoto, M. Suzuki, M. Umeda et al. // Int J. Syst Evol Microbiol.-2002.-Vol.52.-P.841-849. Siqueira J. Molecular detection of black-pigmented bacteria in infection of endodontic origin / J.F. Siqueira, I.N. Roca, J.C. Oliveira, K.R. Santos // J.Endod.-2001.-Vol.27, N9.-P.563-566 Slots J. Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitansin human periodontal diseases / Slots J., Listgarten M. A. // J. Clin. Periodontol.- 1988.-Vol.l5.-P.85-93. Sundqvist G., Microbiologic analysis of teeth with failed endodontic treatment and outcome of conservative re-treatment / G. Sundqvist, D. Figdor, S. Persson, U. Sjogren // Oral Surg. Oral Med. Oral Pathol.-Oral Radiol. Endod.-1998.-Vol.85.-P.86-93. Tabeta K. Toll-Like Receptors Confer Responsiveness to Lipopolysaccharide from Porphyromonas gingivalisin Human Gingival Fibroblasts / K.Tabeta, K.Yamazaki, S. Akashi et al. // Infect.Immun.- 2000.- Vol. 68, No. 6.-P. 3731-3735. Teng Y.-T.A. Periodontal heath and systemic disorders / Y.-T.A. Teng, G.W. Taylor, F. Scannapieco et al. //J.Dent.Assoc.-2002.-Vol.68, N2.-P.188-192. Torabinejad M., Eby W.C., Naidort I.J. Inflammatory and immunological aspects of the pathogenesis of human periapical lesions / Torabinejad M., // J.Endod.-1985.-Vol.11.-P.479. van Winkelhoff A. Porphyromonas(Bacteroides) endodontalis: its role in endodontal infections / van Winkelhoff A.J., van Steenbergen T.J.M., Graaff J. // J.Endod.-1992.-Vol.18.-P.43 1-434. Wallin R.P.A. Heat-shock proteins as activators of the innate immune system / R.P.A. Wallin, A. Lundqvist, S.H. More et al. // Trends Immunol.- 2002.-Vol.23.-P.I30-135. Winkelhoff A.J. Porphyromonas gingivalis, Bacteroides forsythus and other putative periodontal pathogens in subjects with and without periodontal destruction / A.J. van Winkelhoff, B.G. Loos, W.A van der Reijden, U. van der Velden // J.Clin.Periodontol.-2002.-Vol.29.- N11.-P. 1023-1028. Yonezawa H. Arg-gingipain A DNA vaccine induces protective immunity against infection by Porphyromonas gingivalis in a murine model / Yonezawa H. // Infect.Immun.-2001.-Vol.69.-P.2858-2864. Yun P.L. Hydrolysis of interleukin-12 by Porphiromonas gingivalis major cysteine proteinases may affect local gamma interferon accumulation and the Thl or Th2 T-cell phenotype in periodontitis / P.L. Yun, A.A. Decarlo, C. Collyer, N. Hunter // Infect.Immunol.-2001.-Vol.69.- N9.-P.5650-5660. Zambon J. J. Periodontal diseases: microbial factors / Zambon J. J // Ann. Periodontol. -1996. -Vol.l.-P.879-925. Zadeh H.H. Evidence for involvement of superantigens in humanperiodontal diseases: skewed expression of T cell receptor variable regions bygingival T cells / Zadeh H.H., Kreutzer D.L. // Oral Microbiol.Immunol.-1996.-Vol.l 1.-P.88-95.
Publication of the article	«World of Medicine and Biology» №1(24), 2010 year, 136-145 pages, index UDK 616.314.19 – 002-06:612