МОРФОЛОГІЧНА ХАРАКТЕРИСТИКА СТРУКТУРНИХ КОМПОНЕНТІВ НИРОК ЩУРА ПРИ ДІЇ ХАРЧОВИХ ДОБАВОК

Автор(и):

Анотація:

Метою огляду було узагальнити сучасні наукові дані щодо макро- та мікроскопічної організації нирок щура як експериментальної моделі, а також проаналізувати відомі механізми токсичного впливу синтетичного харчового барвника Ponceau 4R на нирки. У роботі систематизовано дані про будову нефрона, ниркового фільтра, канальцевого апарату та особливості кровопостачання нирок щура. Окрему увагу приділено відомостям про цитотоксичність Ponceau 4R, індукцію оксидативного стресу, ушкодження клітин ниркового походження і потенційні ризики тривалого харчового надходження барвника. Наведені дані підтверджують доцільність подальших морфологічних і морфометричних досліджень нефротоксичності Ponceau 4R.

Ключові слова:

нирки щури харчові добавки Ponceau 4R нефротоксичність органи видільної системи оксидативний стрес гістологічний аналіз

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Публікація:

«Світ медицини та біології» Том 22 № 96 (2026) , с. 264-271
УДК 611.61:613.29]-092.9(048.8)

DOI:

https://doi.org/10.26724/2079-8334-2026-2-96-264-271