THE INFLUENCE OF GOITROGENS AND ENVIRONMENTAL FACTORS ON THE REPRODUCTIVE SYSTEM OF WOMEN WITH ENDEMIC THYROID DISEASES

Authors:

Abstract:

To study the dynamics of growth and prevalence of thyroid diseases during pregnancy, childbirth and the postpartum period in women under the influence of endemic iodine deficiency and anthropogenic factors. The analysis of morbidity among pregnant women, complications in childbirth in women of Western Ukraine. The study indicates that the prevalence of endemic goiter in seven regions of Western Ukraine during the gestation period is in direct proportional connection not only with natural iodine deficiency. Special attention is paid to the impact of technogenic pollution, additional goitrogens, iodine radioactive isotopes on thyroid gland morbidity. These findings suggest the need for an integrated approach to the wide prevention of thyroid gland pathology and the systematic monitoring of its effectiveness for improving the reproductive health and reducing perinatal complications.

Keywords:

endemic environmental radiation factors iodine deficiency thyroid homeostasis goiterogenesis pregnancy prevention

References:

1. Balabolkin M. I. Fundamentalnaya i klinicheskaya tireoidologiya : rukovodstvo / M. I. Balabolkin, Ye. M. Klebanova, V. M. Kreminskaya - M. : Meditsina, 2007. - 816 s.
2. Botsyurko V. I. Problema yodnoho defitsytu ta yoho podolannya na Prykarpatti / Botsyurko V. I., Skrypnyk, N. V., Tymkiv I. V., Tymkiv I. S. // Problemy endokrynnoyi patolohiyi. - 2006. - No 3. - S. 84-87.
3. Korzun V. N. Problemy i perspektyvy profilaktyky yododefitsytnykh zakhvoryuvan u naselennya Ukrayiny / V. N. Korzun, A. M . Parats, A. P. Matviyenko // Endokrynolohiya. - 2005. – No. 2. - S. 187-193.
4. Kravchenko V. I. Yododefitsyt tryvaye - zdorov’ya naselennya pohirshuyetsya / V. I. Kravchenko // Mizhnarodnyy endokrynolohichnyy zhurnal. - 2008. – No.6 (18). - S. 9-18.
5. Kurmacheva N. A. Mediko-sotsial'nyye problemy zdorovya materi i rebenka v yododefitsitnom regione i puti ikh resheniya / N. A. Kurmacheva // Ginekologiya. - 2005. – No.7 (3). - C. 146.
6. Mayorov M. V. Beremennost i shchitovidnaya zheleza / M. V. Mayorov // Provizor. - 2009. – No. 3. - S. 47-50.
7. Pankiv V. I. Praktychna tyreoyidolohiya / V. I. Panʹkiv. - Donetsk, 2011. - 224 s.
8. Petunina N.A. Klinicheskiye aspekty yodnoy nedostatochnosti: puti korrektsii / N.A. Petunina // Farmateka.-2006.-No. 17. - S. 64-68.
9. Podolskii V. V. Porushennya reproduktyvnoho zdorovya ta yikh zvyazok zi stanom shchytopodibnoyi zalozy u zhinok fertylnoho viku / V. V. Podolskii, V. YA. Kozar // Zdorove zhenshchyny. - 2009. – No. 5 (41). - S. 107-112.
10. Tyreopatiyi v Karpatskomu rehioni / Sydorchuk I. Y., Pashkovska N. V., Pankiv V. I. [ta in.] - Chernivtsi : Meduniversytet, 2007. - 440 s.
11. Fabri A. Z. Ekoloho-hihiyenichni aspekty poshyrennya endemichnoho zoba v riznykh bioheokhimichnykh zonakh Zakarpattya / A. Z. Fabri // Endokrynolohiya. - 2005. – No. 1. - S. 41-50.
12. Cheban A. K. Neskholasticheskiye tireoidnyye posledstviya Chernobylskoy katastrofy / A. K. Cheban. - K. : Meditsina, 2006. - 198 s.
13. Shilin D. Ye. Akusherskiye aspekty yodnogo defitsita i yego korrektsii: chto novogo? / D. Ye. Shilin // Ginekologiya (prilozheniye k zhurnalu Consilium Medicum). - 2005. – No.7 (5-6). - S. 325-332.
14. Shidlovskii V. O. Yodnyi defitsyt i yododefitsytni zakhvoryuvannya. Posibnyk dlya likariv / V. O. Shidlovskyy, I. M. Deykalo, O. V. Shidlovskii. - K., 2004. - 68 s.
15. Shchitovidnaya zheleza i reproduktivnaya sistema zhenshchiny: posobiye dlya vrachey / Potin V. V. , Krikheli I. O., Loginov A. B., Musayeva T. T. [i dr.] / pod redaktsiyey E. K. Aylamazyan. - SPb.: Iz-vo N-L, 2008. - 48 s.
16. Maternal thyroid autoantibodies during the third trimester and hearing deficits in children: an epidemiologic assessment / Ellen E., Wasserman E., Nelson K. [et al.] // American Journal of Epidemiology. - 2008. - V. 167, No. 6. - P. 701-710.

Publication:

«World of Medicine and Biology» Vol. 13 No. 62 (2017) , с. 66-71
УДК 618.1 – 06:616.441- 036.21]-02

DOI:

https://doi.org/10.26724/2079-8334-2017-4-62-66-71