STUDY OF MARKERS OF ANTIOXIDANT PROTECTION OF THE ORAL CAVITY IN THE ORAL FLUID OF PATIENTS WITH PERI-IMPLANTITIS AGAINST THE BACKGROUND OF THE TREATMENT AND PREVENTION COMPLEX

Authors:

Abstract:

The study was devoted to researching the effect of the treatment and preventive complex on biochemical markers of the antioxidant system in the oral fluid of patients with peri-implantitis. 40 patients with peri-implantitis aged between 25 and 55 years took part in the research. In the oral fluid of patients, the indicator of antioxidant protection of the oral cavity was determined. The therapeutic and prophylactic complex led to a substantial elevation in the antioxidant-prooxidant index, exceeding the levels found in somatically healthy patients after six months of treatment. This antioxidant-prooxidant index elevation suggests a restoration and amplification of non-specific oral cavity resistance, emphasizing the complex's potential to sustain long-term antioxidant defense in patients with peri-implantitis amid concomitant conditions like periodontitis and atherosclerosis.

Keywords:

oral fluid health of the oral cavity implants treatment and prevention complex adult patients

References:

1. Makarenko OA, Khromahina LM, Khodakov IV. Metody doslidzhennya stanu kyshkovyka ta kistok u laboratornykh shchuriv: dovidnyk. Odesa: Odeskyy natsionalnyy universytet im. I.I. Mechnykova, 2022. 81 p. [in Ukrainian].
2. Rohach IM, Keretsman AO, Sitkar AD. Pravylno vybranyy metod statystychnoho analizu – shlyakh do yakisnoyi interpretatsiyi danykh medychnykh doslidzhen. Naukovyy visnyk Uzhhorodskoho universytetu, seriya “Medytsyna”. 2017;2(56):124–128. [in Ukrainian].
3. Adubetska AY, Dienha OV, Dienga AE, Verbytska TH, Shnaider SA, Pyndus TO, et al. Genetic predisposition to peri-implantitis and thrombosis in dental implants. World of Medicine and Biology. 2023;2(84):7–11. doi:10.26724/2079-8334-2023-2-84-7-11.
4. Canullo L, Peñarrocha M, Monje A, Catena A, Wang HL, Peñarrocha D. Association Between Clinical and Microbiologic Cluster Profiles and Peri-implantitis. Int J Oral Maxillofac Implants. 2017;32(5):1054–1064. doi: 10.11607/jomi.6043.
5. Canullo L, Radovanović S, Delibasic B, Blaya JA, Penarrocha D, Rakic M. The predictive value of microbiological findings on teeth, internal and external implant portions in clinical decision making. Clin Oral Implants Res. 2017;28(5):512–519. doi: 10.1111/clr.12828.
6. Darby I. Risk factors for periodontitis & peri-implantitis. Periodontol 2000. 2022;90(1):9–12. doi: 10.1111/prd.12447.
7. Fi C, Wo W. Periodontal disease and systemic diseases: an overview on recent progresses. J Biol Regul Homeost Agents. 2021;35(1 Suppl. 1):1–9.
8. Halstenbach T, Nelson K, Iglhaut G, Schilling O, Fretwurst T. Impact of peri-implantitis on the proteome biology of crevicular fluid: A pilot study. J Periodontol. 2023;94(7):835–847. doi: 10.1002/JPER.22-0461.
9. Lumbikananda S, Srithanyarat SS, Mattheos N, Osathanon T. Oral Fluid Biomarkers for Peri-Implantitis: A Scoping Review. Int Dent J. 2024;74(3):387–402. DOI: 10.1016/j.identj.2023.11.005.
10. Marcantonio C, Nicoli LG, Marcantonio Junior E, Zandim-Barcelos DL. Prevalence and Possible Risk Factors of Peri-implantitis: A Concept Review. J Contemp Dent Pract. 2015;16(9):750–7. doi: 10.5005/jp-journals-10024-1752.
11. Yarov YuYu, Silenko YuI. Efficiency of differentiated long term maintenance treatment in dental implant surgery patients. World of Medicine and Biology. 2018;4(66):136–140. doi: 10.26724/2079-8334-2018-4-66-136-140.
12. Zhuang LF, Watt RM, Mattheos N, Si MS, Lai HC, Lang NP. Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri-implant tissues. Clin Oral Implants Res. 2016;27(1):13–21. doi: 10.1111/clr.12508.

Publication:

«World of Medicine and Biology» Vol. 20 No. 90 (2024) , с. 7-11
УДК [616-053.81+616.314-089.843]:616.31-08-039.71

DOI:

https://doi.org/10.26724/2079-8334-2024-4-90-7-11