BASIC PRINCIPLES OF EXPERIMENTAL SIMULATION OF LIPOSUCTION AND ABDOMINOPLASTY

Authors:

Abstract:

According to forecasts, by 2035, 50 % of the world's population will suffer from obesity, and we aimed to develop effective experimental models for the correction of its consequences, in the form of aesthetic defects of the anterior abdominal wall. By following a diet high in carbohydrates and saturated fat, obesity was achieved in 100 % of experimental animals. To ensure the possibility of conditional extrapolation of the obtained results to people, interventions and their combination were carried out in compliance with the basic principles of clinical operative technique. The rate of postoperative complications ranged from 7.1 % to 14.3 %, and changes in anthropometric parameters affected by obesity achieved aesthetic improvement and were characterized by statistical significance (p<0.05). The result of this work was a step-by-step algorithm with the possibility of dynamic control over functional, physiological, biochemical and pathomorphological changes in the organism of experimental animals. The insignificant number of postoperative complications and the simplicity of the proposed techniques for performing abdominoplasty, liposuction and their combination allow us to recommend the described techniques as effective mechanisms for experimental research into methods of surgical correction of aesthetic defects of the anterior abdominal wall.

Keywords:

liposuction abdominoplasty obesity experiment anterior abdominal wall aesthetic defects

References:

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Publication:

«World of Medicine and Biology» Vol. 20 No. 88 (2024) , с. 225-230
УДК 616-092.9:617.55-089.844

DOI:

https://doi.org/10.26724/2079-8334-2024-2-88-225-230