RATING THE PERFUSION OF THE LARGE INTESTINE SEGMENT IN PATIENTS WITH A HISTORY OF LAPAROSCOPIC TOTAL MESORECTAL EXCISION
Clinical medicine

RATING THE PERFUSION OF THE LARGE INTESTINE SEGMENT IN PATIENTS WITH A HISTORY OF LAPAROSCOPIC TOTAL MESORECTAL EXCISION

Published 2023-04-12

Authors:

S.A. Huseynov
E.H. Azimov
M.J. Sultanova

Abstract:
The purpose of the study was to assess the perfusion of the large intestine segment with the angiography in quality and quantity during the laparoscopic total mesorectal excision. The work was carried out on the basis of the analysis of the results of fluorescent images of 28 patients who were diagnosed with adenocarcinoma of the rectum of various degrees and underwent laparoscopic total mesorectal excision. Using the fluorescence curve, T½max and the time ratio (TR=T½ max/T max) from the graphs, the fluorescence intensity of the colon was assessed as weak, medium or high. Of the patients under our supervision, T½max<18 sec was observed in 75 % of patients, T½max>18 sec–in 21.4 % of patients. In 16.7 % of cases in patients with low perfusion (TR<0.4) who underwent a safe anastomosis, narrowness of the anastomosis was noted, in 33.3 % of cases in patients with average perfusion (0.4, T½max 19.8>, slope 1.7<, the likelihood of complications also increases. These indices are considered independent criteria. The use of quantity indexes as ½T max and TR during the study of perfusion with indocyanine green, assisted in finding the intestinal segment with weak perfusion.
Keywords:
laparoscopic total mesorectal excision fluorescence imaging quantity indices T½max and TR colorectal cancer
References:
  1. Asari SA, Cho MS, Kim NK. Safe anastomosis in laparoscopic and robotic low anterior resection for rectal cancer: a narrative review and outcomes study from an expert tertiary center. Eur J Surg Oncol. 2015 Feb;41(2):175–85. doi: 10.1016/j.ejso.2014.10.060.
  2. Blanco-Colino R, Espin-Basany E. Intraoperative use of ICG fluorescence imaging to reduce the risk of anastomotic leakage in colorectal surgery: a systematic review and meta-analysis. Tech Coloproctol. 2018 Jan;22(1):15–23. doi: 10.1007/s10151-017-1731-8.
  3. Boni L, David G, Dionigi G, Rausei S, Cassinotti E, Fingerhut A. Indocyanine green-enhanced fluorescence to assess bowel perfusion during laparoscopic colorectal resection. Surg Endosc. 2016 Jul;30(7):2736–42. doi: 10.1007/s00464-015-4540-z.
  4. Degett TH, Andersen HS, Gögenur I. Indocyanine green fluorescence angiography for intraoperative assessment of gastrointestinal anastomotic perfusion: a systematic review of clinical trials. Langenbecks Arch Surg. 2016 Sep;401(6):767–75. doi: 10.1007/s00423-016-1400-9.
  5. Foppa C, Denoya PI, Tarta C, Bergamaschi R. Indocyanine green fluorescent dye during bowel surgery: are the blood supply "guessing days" over? Tech Coloproctol. 2014 Aug;18(8):753–8. doi: 10.1007/s10151-014-1130-3.
  6. Jafari MD, Wexner SD, Martz JE, McLemore EC, Margolin DA, Sherwinter DA, et al. Perfusion assessment in laparoscopic left-sided/anterior resection (PILLAR II): a multi-institutional study. J Am Coll Surg. 2015 Jan;220(1):82–92. doi: 10.1016/j.jamcollsurg.2014.09.015.
  7. James DR, Ris F, Yeung TM, Kraus R, Buchs NC, Mortensen NJ, et al. Fluorescence angiography in laparoscopic low rectal and anorectal anastomoses with pinpoint perfusion imaging--a critical appraisal with specific focus on leak risk reduction. Colorectal Dis. 2015 Oct;17 Suppl 3:16–21. doi: 10.1111/codi.13033.
  8. Kamiya K, Unno N, Miyazaki S, Sano M, Kikuchi H, Hiramatsu Y, et al. Quantitative assessment of the free jejunal graft perfusion. J Surg Res. 2015 Apr;194(2):394–399. doi: 10.1016/j.jss.2014.10.049.
  9. Kim JC, Lee JL, Park SH. Interpretative Guidelines and Possible Indications for Indocyanine Green Fluorescence Imaging in Robot-Assisted Sphincter-Saving Operations. Dis Colon Rectum. 2017 Apr;60(4):376–384. doi: 10.1097/DCR.0000000000000782.
  10. Kin C, Vo H, Welton L, Welton M. Equivocal effect of intraoperative fluorescence angiography on colorectal anastomotic leaks. Dis Colon Rectum. 2015 Jun;58(6):582–7. doi: 10.1097/DCR.0000000000000320.
  11. Kyrian OA, Derkach IA, Dorofeyev AE, Rudenko MM. Changes in the intestinal microbiota in patients with ulcerative colitis and irritable bowel syndrome combined with urolithiasis. World of medicine and biology. 2021; 3(77):77–81.doi: 10.26724/2079-8334-2021-3-77-77-81
  12. McDermott FD, Heeney A, Kelly ME, Steele RJ, Carlson GL, Winter DC. Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks. Br J Surg. 2015 Apr;102(5):462–79. doi: 10.1002/bjs.9697.
  13. Protyniak B, Dinallo AM, Boyan WP Jr, Dressner RM, Arvanitis ML. Intraoperative indocyanine green fluorescence angiography – an objective evaluation of anastomotic perfusion in colorectal surgery. Am Surg. 2015 Jun;81(6):580–4. doi: 10.1177/000313481508100621.
  14. Ryu S, Yoshida M, Hironori O, Tsutsui N, Suzuki N, Ito E, et al. Intraoperative ICG fluorescence contrast imaging of the main artery watershed area in colorectal cancer surgery: Report of a case. Int J Surg Case Rep. 2016; 26:176–8. doi: 10.1016/j.ijscr.2016.06.009. E
  15. Wada T, Kawada K, Takahashi R, Yoshitomi M, Hida K, Hasegawa S, et al. ICG fluorescence imaging for quantitative evaluation of colonic perfusion in laparoscopic colorectal surgery. Surg Endosc. 2017 Oct;31(10):4184–4193. doi: 10.1007/s00464-017-5475-3.
Publication:
«World of Medicine and Biology» Vol. 19 No. 84 (2023) , с. 60-65
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