THE INFLUENCE OF ANXIETY LEVEL AND PAST COVID-19 ON SLEEP QUALITY AND INSOMNIA SEVERITY
Clinical medicine

THE INFLUENCE OF ANXIETY LEVEL AND PAST COVID-19 ON SLEEP QUALITY AND INSOMNIA SEVERITY

Published 2022-11-30

Authors:

D.I. Boiko
A.I. Zhyvotovska
A.M. Skrypnikov

Abstract:
Based on recent studies, we put forward a hypothesis about the synergistic effect of anxiety disorders and previous COVID-19 on the deterioration of the quality of sleep and occurring of insomnia. The purpose of the study was to investigate the impacts of anxiety disorders, and COVID-19 on anamnesis and its combined effect on sleep disturbances. We conducted a case-control study, which included 60 patients, who were divided into 3 groups depending on the occurrence of anxiety disorders and COVID-19 in their medical history during the last 6 months. Patients were assessed by the Beck anxiety inventory, Pittsburgh Sleep Quality Index, and the Insomnia Severity Index. We found a worsening sleep quality and a higher frequency of insomnia in patients with COVID-19. Along with this, concomitant anxiety disorders worsened both the quality of sleep and the level of insomnia in these respondents. It was determined that patients with an anxiety disorder with a history had a lower subjective assessment of sleep quality, higher sleep latency, and more pronounced diurnal dysfunction, while patients without a history had better sleep efficiency and a lower frequency of sleeping pills. Anxiety disorders and having experienced COVID-19 are associated with poorer sleep quality and more severe insomnia. Their combination significantly reduces the quality of sleep and increases the degree of insomnia. These findings suggest a potential role for COVID-19 in exacerbating the association between anxiety and sleep disorders.
Keywords:
anxiety mood disorders sleep disorders insomnia sleep quality COVID-19
References:
  1. Blake MJ, Trinder JA, Allen NB. Mechanisms underlying the association between insomnia, anxiety, and depression in adolescence: Implications for behavioral sleep interventions. Clin Psychol Rev 2018;63:25–40. https://doi.org/10.1016/j.cpr.2018.05.006.
  2. Boiko DI, Skrypnikov AM, Shkodina AD, Hasan MM, Ashraf GM, Rahman MH. Circadian rhythm disorder and anxiety as mental health complications in post-COVID-19. Environ Sci Pollut Res 2022. https://doi.org/10.1007/s11356-021-18384-4.
  3. Deng J, Zhou F, Hou W, Silver Z, Wong CY, Chang O, et al. The prevalence of depression, anxiety, and sleep disturbances in COVID‐19 patients: a meta‐analysis. Ann N Y Acad Sci 2021;1486:90–111. https://doi.org/10.1111/nyas.14506.
  4. Dmitrzak-Węglarz M, Pawlak J, Wiłkość M, Miechowicz I, Maciukiewicz M, Ciarkowska W, et al. Chronotype and sleep quality as a subphenotype in association studies of clock genes in mood disorders. Acta Neurobiol Exp (Wars) 2016;76:32–42. https://doi.org/10.21307/ane-2017-003.
  5. Hussain H, Ahmad S, Tsagkaris C, Asghar Z, Aborode AT, Essar MY, et al. Effect of Sunlight on SARS-CoV-2: Enlightening or Lighting? Can J Med 2021;3:6–9. https://doi.org/10.33844/cjm.2021.60498.
  6. Kaidashev I, Shlykova O, Izmailova O, Torubara O, Yushchenko Y, Tyshkovska T, et al. Host gene variability and SARS-CoV-2 infection: A review article. Heliyon 2021;7:e07863. https://doi.org/10.1016/j.heliyon.2021.e07863.
  7. Kocevska D, Blanken TF, Van Someren EJW, Rösler L. Sleep quality during the COVID-19 pandemic: not one size fits all. Sleep Med 2020;76:86–8. https://doi.org/10.1016/j.sleep.2020.09.029.
  8. Medina-Ortiz O, Araque-Castellanos F, Ruiz-Domínguez LC, Riaño-Garzón M, Bermudez V. Trastornos del sueño a consecuencia de la pandemia por COVID-19. Rev Peru Med Exp Salud Publica 2020;37:755–61. https://doi.org/10.17843/rpmesp.2020.374.6360.
  9. Semyachkina-Glushkovskaya O, Mamedova A, Vinnik V, Klimova M, Saranceva E, Ageev V, et al. Brain Mechanisms of COVID-19-Sleep Disorders. Int J Mol Sci 2021;22:6917. https://doi.org/10.3390/ijms22136917.
  10. Sher L. COVID-19, anxiety, sleep disturbances and suicide. Sleep Med 2020;70:124. https://doi.org/10.1016/j.sleep.2020.04.019.
  11. Shevlin M, Nolan E, Owczarek M, McBride O, Murphy J, Gibson Miller J, et al. COVID‐19‐related anxiety predicts somatic symptoms in the UK population. Br J Health Psychol 2020;25:875–82. https://doi.org/10.1111/bjhp.12430.
  12. Silva VM, Magalhaes JE de M, Duarte LL. Quality of sleep and anxiety are related to circadian preference in university students. PLoS One 2020;15:e0238514. https://doi.org/10.1371/journal.pone.0238514.
  13. Uddin MS, Tewari D, Mamun A Al, Kabir MT, Niaz K, Wahed MII, et al. Circadian and sleep dysfunction in Alzheimer’s disease. Ageing Res Rev 2020;60:101046. https://doi.org/10.1016/j.arr.2020.101046.
  14. Voitsidis P, Gliatas I, Bairachtari V, Papadopoulou K, Papageorgiou G, Parlapani E, et al. Insomnia during the COVID-19 pandemic in a Greek population. Psychiatry Res 2020;289:113076. https://doi.org/10.1016/j.psychres.2020.113076.
  15. Zhyvotovska L, Boiko D, Bodnar L, Shinder V. Effecacy evaluation of treatment and rehabilitation in patients with the first psychotic episode with biological rhythms. Sci Med Sci 2017:15–9. https://doi.org/10.15587/2519-4798.2017.97026.
Publication:
«World of Medicine and Biology» Vol. 18 No. 82 (2022) , с. 31-35
УДК 616.8-009.836:619.9