COMPARISON OF THE EFFECT OF ANTISEPTICS BASED ON DECAMETHOXINE, CHLORHEXIDINE BIGLUCONATE AND IODOFORM ON THE ADHESIVE POTENTIAL OF BACTERIA OF THE GENUS KOCURIA SPP

Authors:

Abstract:

Antiseptics can block the adhesion of bacteria, thus facilitating the course of the purulent-inflammatory process. Therefore, we investigated the adhesive properties of clinical isolates of the genus Kocuria isolated from the oral cavity of patients with infectious-inflammatory post-extraction complications. Remedies based on decamethoxine, chlorhexidine bigluconate and iodoform were used as test antiseptics. The adhesive properties of clinical isolates under the action of remedies based on decamethoxine, chlorhexidine bigluconate and iodoform were determined by V.I. Brillis. The adhesion index values of microorganisms of clinical isolates of the genus Kocuria under the action of subbacteriostatic concentration of remedy based on decamethoxine were 1.6 times (p<0.05) and 2.1 times (p<0.05) lower compared to those of the adhesion index of microorganisms after the action of remedies based on chlorhexidine bigluconate subbacteriostatic concentrations and iodoform respectively. In the presence of remedy based on chlorhexidine bigluconate SBsC, relative to the clinical isolates Kocuria kristinae 1 and Kocuria kristinae 2, IAM indices increased 1. 3 times, and IAM indices of Kocuria rosea increased 1.1 times compared to the IAM indices of the controls of these isolates. Considering the results of action remedy based on iodoform SBsC on clinical isolates Kocuria kristinae 1 and Kocuria kristinae 2, IAM increased in 2.1 times and in 1.5 times, IAM of clinical isolate Kocuria rosea also increased, but in 1.4 times, considering the control cultures.

Keywords:

adhesion of microorganisms pathogenic factors antiseptics clinical isolates purulent-inflammatory process

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Publication:

«World of Medicine and Biology» Vol. 18 No. 82 (2022) , с. 217-221
УДК 616-002.3:615.28

DOI:

https://doi.org/10.26724/2079-8334-2022-4-82-217-221