FUNCTIONAL CONDITION OF KIDNEYS IN PATIENTS WITH ARTERIAL HYPERTENSION IN COMBINATION WITH TYPE 2 DIABETES MELLITUS

Authors:

Abstract:

The purpose of the study was to clarify the diagnostic significance of neutrophil gelatinase-associated lipocalin and cystatin C in the blood of patients with arterial hypertension and type 2 diabetes mellitus and their correlation with intrarenal hemodynamic parameters. It was installed that in comparison with persons without diabetes in patients with arterial hypertension and type 2 diabetes mellitus at the stage of preclinical kidney damage found a more significant increase in neutrophil gelatinase-associated lipocalin and cystatin C in the blood. This allows us to consider these indicators as diagnostic manifestations of early detection of diabetic nephropathy. It was determined that a significant decrease in the final diastolic arterial blood flow velocities and a significant increase in the resistance index are diagnostic markers of morpho-functional changes in the kidneys during duplex scanning of the renal arteries in patients with arterial hypertension and type 2 diabetes mellitus.

Keywords:

neutrophil gelatinase-associated lipocalin cystatin C duplex scanning of renal arteries arterial hypertension type 2 diabetes mellitus

References:

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Publication:

«World of Medicine and Biology» Vol. 18 No. 80 (2022) , с. 24-29
УДК 616.61-008.6-07:[616.12-008.331.1+616.379-008.64]

DOI:

https://doi.org/10.26724/2079-8334-2022-2-80-24-29