RETROSPECTIVE ANALYSIS OF TREATMENT EFFICACY IN PATIENTS WITH CHRONIC WOUNDS

Authors:

Abstract:

It is estimated that in developed countries from 1 to 2 % of the population will suffer from chronic wounds throughout their life. The study included the retrospective analysis data on the case histories of 75 patients (40 (53 %) women and 35 (47 %) men who were divided into 8 groups depending on the etiological factor. The other determining factor was the use of local negative pressure in their treatment. In all groups active surgical intervention was used, the preparation of the wound for surgical intervention with the help of negative pressure was faster. As a result, the time of the patient’s staying at the in–patient department reduced and the percentage of autotransplants survival increased. Results of the analysis showed that the use of local vacuum therapy caused statistically significant difference in the mean time of treatment between some groups of patients compared to other groups. The number of eliminated chronic wounds is also statistically significant.

Keywords:

chronic wounds retrospective analysis etiological factor local negative pressure

References:

1. Herasymchuk PO, Deykalo IM, Vlasenko VH, Fira DB, Pavlyshyn AV. Vykorystannya vakuum-terapiyi v likuvanni ran u khvorykh na syndrom diabetychnoyi stopy. MÉZH. 2016; 2(74):124-9. [in Ukrainian]
2. Gain YuM, Gerasimenko MA, Shahraj SV, Hryshchanovich VYa, Gain MYu, Bordakov PV. Innovatsionnye printsipy kompleksnogo lecheniya khronicheskikh ran. Innovatsionnye tekhnologii v meditsine. 2017; 5(4):223-42. [in Russian]
3. Glukhov AA, Aralova MV. Patofiziologiya dlitelno nezazhivayushchikh ran i sovremennyye metody stimulyatsii ranevogo protsessa. Novosti khirurgii. 2015; 23(60):573-9. [in Russuian]
4. Nor NM, Slesarenko SV, Trofimov MV, SlesarenkoKS, Korpusenko OI. Zastosuvannya vakuum-terapiyi u kompleksi likuvannya khronichnykh ran nyzhnikh kintsivok. Klinichna khirurhiya. 2017; 3: 39-41. [in Ukrainian]
5. Obolenskiy VN. Sovremennyye metody lecheniya khronicheskikh ran. Meditsinskiy sovet. 2016; 10:148-154. [in Russian]
6. Slavnikov IA, Dundarov ZA, Yarec YuI. Otsenka effektivnosti sposobov podgotovki k plasticheskomu zakrytiyu khronicheskikh ran u patsientov s sakharnym dіabetom. Zhurnal Grodnenskogo gosudarstvennogo meditsinskogo universiteta. 2018; (6):735-9. DOI: 10.25298/2221-8785-2018-16-6-735-739 [in Russian]
7. Cwaliński J, Paszkowski J, Banasiewicz T. New perspectives in the treatment of hard-to-heal wound. Negative Pressure Wound Therapy Journal. 2018; 5(4):10-2.
8. Demidova-RiceTN, Hamblin MR, Herman IM. Acute and impaired wound healing:pathophysiology and current methods for drug delivery, part 1: normal and chronicwounds: biology, causes, and approaches to care. Adv Skin Wound Care. 2012 Jul; 25(7):304-14. doi: 10.1097/01.ASW.0000416006.55218.d0.
9. Järbrink K, Ni G, Sönnergren H, Schmidtchen A, Pang C, Bajpai R, Car J. Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review. Syst Rev. 2016 Sep 8; 5(1):152. doi:10.1186/s13643-016-0329-y.
10. Maruccia M, Onesti MG, Sorvillo V, Albano A, Dessy LA, Carlesimo B, et al. An alternative treatment strategy for complicated chronic wounds: Negative Pressure Therapy over Mesh Skin Graft. Biomed Res Int. 2017; 8395219.
11. doi: 10.1155/2017/8395219.
12. Uccioli L, Izzo V, Meloni M, Vainieri E, Ruotolo V, Giurato L. Non-healing foot ulcers in diabetic patients: general and local interfering conditions and management options with advanced wound dressings. J Wound Care. 2015; 24(Suppl 4b):35-42. DOI: 10.12968/jowc.2015.24.Sup4b.35

Publication:

«World of Medicine and Biology» Vol. 17 No. 75 (2021) , с. 69-73
УДК 616-001.4-085.032-039.32

DOI:

https://doi.org/10.26724/2079-8334-2021-1-75-69-73