PATHOMORPHOLOGICAL CHANGES OF THE OPTICAL NERVE INTRACRANIAL PART IN DIABETES MELLITUS

Authors:

Abstract:

The work is devoted to the study of morphological changes in the optic nerve, mainly its intracranial part, in diabetic microangiopathy. It has been shown that diabetic microangiopathy is accompanied by proliferation of capillary endotheliocytes, resulting in narrowing or obliteration of the blood vessels lumen. In its turn, this leads to ischemia of nerve fibers with the development of dystrophic changes and partial or complete destruction of astrocytes and oligodendrocytes. Obviously, in diabetes mellitus, these processes also occur in the optic nerve tissues. Severe form of diabetic optic nerve microangiopathy is similar to the proliferative form of retinopathy by its morphological features.

Keywords:

diabetic retinopathy optic nerve morphology

References:

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Publication:

«World of Medicine and Biology» Vol. 17 No. 75 (2021) , с. 201-205
УДК 611.843+616-053

DOI:

https://doi.org/10.26724/2079-8334-2021-1-75-201-205