HISTOLOGICAL CHANGES IN LIVER AND KIDNEYS IN EXPERIMENTAL TYPE 2 DIABETES MELLITUS AND ITS CORRECTION BY ADMINISTRATION OF GALEGA OFFICINALIS L. PHYTOCOMPOSITIONS

Authors:

Abstract:

The experimental studies of the morphological state of the white rats’ kidney and liver in conditions of the simulated Type 2 diabetes mellitus and the use of pharmaceutical preparation comprising Galega officinalis L. and Vaccinium myrtillus , as well as administration of «Galevit» liposomal formulation have been carried out. In the group of animals without correction the drastic destructive-degenerative damage to all structural components of the studied bodies and significant vascular disorders has been found. Application of the remedial pharmaceutical preparation comprising Galega officinalis L. and Vaccinium myrtillus has a positive effect on morphofunctional state of the liver and kidneys of laboratory animals, especially the administration of the «Galevit» liposomal formulation. The degree of the reparatory processes in the studied organs in experimental type 2 diabetes mellitus shows that the new «Galevit» composition has more apparent positive effect as compared to the pharmaceutical preparation comprising Galega officinalis L. and Vaccinium myrtillus.

Keywords:

liver kidneys Type 2 diabetes mellitus Galega officinalis L. Vaccinium myrtillus liposomal form

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Publication:

«World of Medicine and Biology» Vol. 14 No. 63 (2018) , с. 133-136
УДК 616.37-091.8-02:616.379-008.64-085.322

DOI:

https://doi.org/10.26.724/2079-8334-2018-1-63-133-136