ACUTE CORONARY SYNDROME: EFFECT OF MYOCARDIAL REVASCULARIZATION AND COMPLEX THERAPY ON CARDIAC REMODELING, SYSTOLIC-DIASTOLIC DYSFUNCTION AND CARDIAC COMPLICATIONS

Authors:

Abstract:

The article presents the results of a long study of the effect of myocardial revascularization, bisoprolol, perindopril and antiplatelet drugs on the status and function of the myocardium and for cardiovascular disease. In examined patients after myocardial revascularization, and prolonged use of drug treatment caused a decrease eccentric left ventricular hypertrophy, and marked increase in angina attacks and symptoms of heart failure, although there was a slight decrease in ventricular fibrillation, atrial fibrillation, AV - blockades and left bundle branch block.

Keywords:

acute coronary syndrome heart remodeling invasive and drug therapy

References:

1. Denesyuk O. V. Dinamika stupeniv remodelyuvannya, sistolo-diastolichnoyi disfunktsiyi livogo shlunochka pri nestabilniy stenokardiyi pid vplivom optimalnogo trivalogo likuvannya / O. V. Denesyuk // Visnik problem biologiyi ta meditsini. – 2015. – No.1(118). – S. 121-126.
2. Matova E. A. Desyatiletnyaya dinamika pokazateley diastolicheskoy funktsii levogo zheludochka u bolnyih gipertonicheskoy boleznyu / E. A. Matova, S. V. Pavlenko, V. P. Svischenko [i dr.] // Ukr. kardIologIch. zhurnal – 2011. – No.1. – S. 60-65.
3. Regionalni mediko-sotsialni problemi hvorob sistemi krovoobigu. Dinamika ta analiz (Analitichno-statistichniy posibnik) /Pid red. V.M. Kovalenko. – K., -2013. – 240 s.
4. Rekomendatsiyi ESC/EACTS po revaskulyarizatsiyi miokarda 2014 // Ros. kardiol. zhurnal. – 2015. – No.2 (48). – S. 5-84.
5. Eichstaedi H. Regresion of the ventricular hypertrophy / H. Eichstaedi, R.S. Schroder, W. Autterman // J. Cargiovasc. Pharmacol. – 1992. – Vol. 19, - № 6. – P. 55-61.
6. Freemantle N. Beta-blocade after myocardial infarction: systematic revien and meta regression analysis /N. Freemantle, J. Cleland, P. Yonng [et al.] // Br. Med. Journal. – 1999. – Vol. 318. – P. 1730-1737.
7. Shekelle P.G. Efficaci of angiotensin converting enzyme inhibitors and beta-blochers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status: a meta-analysis of major clinical trials / P.G. Shekelle, W.W., Rich S.C., Morton [et al.] // J. Am. Coll. Cardiol. – 2003. – Vol. 41. - P. 1529-1538.
8. Terpstra W.F. Long – term effects of amiodarone and lisinopril on left ventricular mass and diastolic function in elderly, previously untreated hypertensive patiens: the ELVERA trial / W.F. Terpstra, J.F. May, A.J. Smit [et al.] // J. Hypertens. – 2001. – N19 (2). - P. 303-309.
9. Zanchetti A. Comparative effects of rhe ACE inhibitor fosinopril and the calcium antagonistamlodipine on left ventricular hypertrophy and urinal albumin excretion in hypertensive patiens.Results of FOAM, a multicenter European Study / A. Zanchetti, L.M. Ruilope, C. Cuspidi [et al.] // Hypertens. – 2001. – Vol. 19 (Suppl. 2). - 92 р.

Publication:

«World of Medicine and Biology» Vol. 12 No. 55 (2016) , с. 35-39
УДК [616.127-005.8+615.221+616.12-073.7]: 616-036.86.-047.7