IN VIVO EXPERIMENTAL STUDY OF MANUKA ESSENTIAL OIL ANTIBACTERIAL PROPERTIES

Authors:

Abstract:

It was found using experiments in vivo on the model of burn Pseudomonas infection in mice that the Manuka essential oil showed a marked antibacterial effect, accelerated reparative processes in the wound and reduced the treatment time of experimental wound infection by 4-6 days or 31-40%.

Keywords:

Manuka essential oil experimental burn Pseudomonas infection

References:

1. Alekseev A. A. Mikrobiologicheskaya otsenka effektivnosti sovremennyih antimikrobnyih preparatov dlya mestnogo lecheniya ozhogovyih ran / A. A. Alekseev, A.E. Bobrovnikov, R.P. Terehova [i dr.] // Kombustiologiya. – 2009. – No. 37. – S. 17-21.
2. Alekseev A.A. Mestnoe ispolzovanie antimikrobnyih sredstv dlya lecheniya ozhogovyih ran / A.A. Alekseev, A.E. Bobrovnikov, M.G. Krutikov // Kombustiologiya. – 2011. – No. 45. – S. 25-32.
3. Krutikov M. G. Antibiotikoprofilaktika v kombustiologii / M. G. Krutikov, A. E. Bobrovnikov // Kombustiologiya. – 2005. – No. 4. – S. 34-37.
4. Minuhin V.V. Ustroystvo dlya naneseniya dozirovannogo ozhoga melkim zhivotnyim / V.V. Minuhin, V.G. Shamray, G.I. Gubina-Vakulik // Med. referat. zhurn. – 1985. – Razd. 4. – No. 12. – Publ. 3621. –66 s.
5. Minuhin V.V. Vivchennya protimIkrobnoyi aktivnosti efirnoyi oliyi manuki ta yiyi kombinatsiy z antibiotikami po vidnoshennyu do zbudnikiv opikovoyi infektsiyi v doslidah in vitro / V.V. Minuhin, N.I. Kovalenko, V.L. Tkachenko [ta in.] // Eksperimentalna i klinichna meditsina. - 2013. – No. 3. – S. 14-18.
6. Soldatchenko S.S. Profilaktika i lechenie zabolevaniy efirnyimi maslami / S.S. Soldatchenko, G.F. Kaschenko // – Simferopol: Tavrida, - 2000. – 160 s.
7. Fistal E.Ya. Kombustiologiya / E.Ya. Fistal, G.P. Kozinets, G.E. Samoylenko [i dr.] // – Donetsk, - 2006. – 236 s.
8. Reichling J.Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties / J. Reichling, P. Schnitzler, U. Suschke [et al.] // Forsch Komplementmed. – 2009. – Vol. 16, № 2. – Р. 79-90.
9. Tairawhiti manuka oil. Режим доступу: http://www.manuka-oil.com/antimicro.htlm.

Publication:

«World of Medicine and Biology» Vol. 12 No. 55 (2016) , с. 146-148
УДК 577.18:57.085:547.913:582.883