INFLUENCE OF INTRAFETAL INJECTION OF STAPHYLOCOCCAL ANATOXIN ON MASS INDICES OF INTERNAL ORGANS OF RATS IN POSTNATAL PERIOD

Authors:

Abstract:

Undifferentiated сonnective tissue dysplasia now is one of the insufficiently studied problems in medicine. Previous researches showed that intrafetal antigen injection can be used for modeling this condition, which leads to changes in morphogenesis rates and terms of fetal organs and tissues and it is manifested in visceromegaly – one of the vivid phenotypic manifestations of undifferentiated connective tissue dysplasia syndrome. Thus, it was found that after prenatal antigen influence of staphylococcal anatoxin signs of visceromegaly develop in rats, which is the manifestation of undifferentiated connective tissue dysplasia syndrome.

Keywords:

staphylococcal anatoxin prenatal influence heart liver kidney visceromegaly

References:

1. Arsentyev V. G. Poliorgannyie narusheniya pri displaziyah soedinitelnoy tkani u detey i podrostkov / V. G. Arsentyev, T. I. Arzumanova, M. V. Aseyev [i dr.] // Pediatriya. – 2009. — T. 87, No 1. — S. 135-138.
2. Voloshin N. A. Vistseromegaliya novorozhdennyih: morfologicheskie aspekty / N.A. Voloshin, E.A. Grigoreva, M. B. Vovchenko [i dr.] // – Kharkiv: HDMU, - 2004.- 123 s.
3. Voloshin N. A. Vnutriutrobnaya antigennaya stimulyatsiya kak model dlya izucheniya simptomokompleksa vistseromegalii / N. A. Voloshin, E. A. Grigoreva, M. S. Scherbakov // Tavricheskiy mediko-biologicheskiy vestnik. – 2006. – T. 9, No4. – S. 57–59.
4. Voloshin N. A. Eksperimentalnaya model razvitiya sindroma nedifferentsirovannoy displazii soedinitelnoy tkani / N. A. Voloshin, E. A. Grigoreva // Patologiya. – 2009. – T. 6, No1. – S. 39–42.
5. Lebedinets O. M. Osoblivosti dynamiky masy tila i sertsya schuriv pislya vplyvu antigeniv v antenatalnomu periodi / O. M. Lebedinets, M. A. Voloshyn, Yu. G. Reznichenko // Tavricheskiy mediko-biologicheskiy vestnik. – 2013. – T. 16, No1, ch. 1 (61) – S. 127–131.
6. Tsimbalista O. L. Syndrom nedyferentsiyovanoyi displaziyi spoluchnoyi tkanyny u ditey, hvoryh na uskladnenu pozalikarnyanu pnevmoniyu / O. L. Tsimbalista, O. I. Gavrylyuk // Zdorovye rebenka. – 2011. – No 3(30). – S. 52-54.
7. Chugin S. V. Vliyanie vnutriutrobnogo vvedeniya antigena na formirovanie limfoidnoy tkani parenhimatoznyih organov krys v rannem postnatalnom periode / S. V. Chugin, M. S. Scherbakov, M. B. Vovchenko // Ukrayinskiy morfologichniy almanah. – 2010. – T. 8, No 2. – S. 225-227.
8. Tong S.Y.C. Colonization, Pathogenicity, Host Susceptibility and Therapeutics for Staphylococcus aureus: What is the Clinical Relevance? / Steven Y.C. Tong, Luke F. Chen [et al.] // Semin Immunopathol. – Mar - 2012. – № 34(2). – P. 185–200.

Publication:

«World of Medicine and Biology» Vol. 10 No. 47 (2014) , с. 90-93
УДК 611.013.9:[615.371:579.861]:611.1/.6 – 026.53] – 053.31