Clinical medicine
SCREENING FOR RISK FACTORS FOR THE DEVELOPMENT OF CARIES
Published
2026-02-04
Authors:
NB
SP
DZ
ZN
IT
OG
OP
- Abstract:
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Dental caries remains a widespread chronic disease requiring effective risk assessment strategies. The purpose of the study was to identify risk factors for caries development and progression in young adults. The study involved 26 dental students aged 19–20 years, divided into three groups: caries-free, compensated caries, and subcompensated caries. Complex examination included assessment of salivary flow rate, viscosity, and pH, and plaque age using indicating tablets, as well as microscopic analysis of Gram-stained dental plaque. The results showed that salivary flow rate and pH (6.0–7.0) were within physiological norms for all groups. However, patients with caries exhibited increased salivary viscosity and a prevalence of mature dental plaque (>48 hours). Microbiological analysis revealed a dominance of Gram-positive cocci, morphologically similar to Streptococcus species, in the plaque of caries-active individuals. It is concluded that local factors, such as salivary viscosity and biofilm maturity, are critical determinants of risk even when general salivary parameters are normal.
- Keywords:
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dental caries risk factors saliva salivary viscosity dental plaque oral microbiota
- References:
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- Council for International Organizations of Medical Sciences (CIOMS). International Ethical Guidelines for Health-related Research Involving Humans, Guideline 15: Research involving vulnerable persons and groups. Geneva: CIOMS; 2023.
- Dawes C, Wong DTW. Role of saliva and salivary diagnostics in the advancement of oral health. J Dent Res. 2019;98(2):133-141. doi: 10.1177/0022034518816961.
- Fejerskov O, Nyvad B, Kidd EAM. Dental Caries: The Disease and Its Clinical Management. 4th ed. Oxford: Wiley Blackwell; 2023.
- Humphrey SP, Williamson RT. Saliva: diagnostic and protective functions. Dent Clin North Am. 2020;64(2):291-305. doi: 10.1016/j.cden.2019.11.002.
- Lamont RJ, Koo H, Hajishengallis G. The oral microbiota: dynamic communities and host interactions. Nat Rev Microbiol. 2018;16(12):745-759. doi: 10.1038/s41579-018-0089-x.
- Marsh PD, Zaura E. Dental biofilm: ecological interactions in health and disease. J Clin Periodontol. 2017;44(S18): S12-S22. doi: 10.1111/jcpe.12679.
- Ministry of Health of Ukraine. Clinical guideline based on evidence "Dental caries" (Clinical Guideline KN 2024-869). Kyiv: Ministry of Health of Ukraine; 23 May 2024. Available at: https://www.dec.gov.ua/wp-content/uploads/2024/05/2024_kn_kariyes_zubiv.pdf.
- Pedersen AML, Sorensen CE, Proctor GB, Carpenter GH. Salivary secretion in health and disease. J Oral Rehabil. 2021;48(8):955-969. doi: 10.1111/joor.13189.
- Samaranayake LP. Essential Microbiology for Dentistry. 5th ed. Edinburgh: Elsevier; 2018.
- Schwendicke F, Splieth C, Breschi L, et al. When to intervene in the caries process? An expert Delphi consensus statement. Clin Oral Investig. 2020;24(10):3315-3321. doi: 10.1007/s00784-020-03269-6.
- World Medical Association. Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191-2194. doi:10.1001/jama.2013.281053.
- Publication:
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«World of Medicine and Biology»
Vol. 22 No. 1 (2026)
, с. 41-45
УДК 616.314-002.4-02./-039.36:616-07
How to Cite
SCREENING FOR RISK FACTORS FOR THE DEVELOPMENT OF CARIES. (2026). World of Medicine and Biology, 22(1), 41-45. https://doi.org/10.26724/2079-8334-2026-1-95-41-45
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