CORRECTION OF INDICATORS OF MINERAL METABOLISM IN THE ORAL FLUID OF PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS, OSTEOPENIA AND OSTEOPOROSIS USING A THERAPEUTIC AND PROPHYLACTIC COMPLEX
Clinical medicine

CORRECTION OF INDICATORS OF MINERAL METABOLISM IN THE ORAL FLUID OF PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS, OSTEOPENIA AND OSTEOPOROSIS USING A THERAPEUTIC AND PROPHYLACTIC COMPLEX

Published 2026-02-04

Authors:

Y.V. Horokhivska
Odessa National Medical University image/svg+xml
https://orcid.org/0009-0008-0313-2697
Y.M. Hurtova
State Establishment "The Institute of stomatology and maxilla-facial surgery National academy of medical sciences of Ukraine"
https://orcid.org/0009-0001-7610-782X
O.V. Dienha
State Establishment "The Institute of stomatology and maxilla-facial surgery National academy of medical sciences of Ukraine"
https://orcid.org/0000-0002-8630-9943
M.I. Baleha
Uzhhorod National University image/svg+xml
https://orcid.org/0000-0001-8440-1298
Zh.O. Novikova
Odessa National Medical University image/svg+xml
https://orcid.org/0000-0002-3930-7929
Yu.V. Demianchuk
Uzhhorod National University image/svg+xml
https://orcid.org/0009-0005-3566-2199
D.S. Shnaider
State Establishment "The Institute of stomatology and maxilla-facial surgery National academy of medical sciences of Ukraine"
https://orcid.org/0009-0001-5936-6547

Abstract:
The study devoted to evaluation the effect of a therapeutic complex of drugs on indicators of mineral metabolism – calcium and inorganic phosphorus concentrations in the oral fluid of patients with chronic generalized periodontitis against a background of osteopenia and osteoporosis. Thirty-five adults (25–55 years) were allocated to three cohorts: an intact healthy control group, a comparison group receiving guideline-based mechanical and pharmacological periodontal therapy, and a main group receiving the same standard therapy supplemented with the therapeutic-prophylactic complex. Findings indicate that the proposed therapeutic complex of drugs exerts a pronounced mineralizing effect and improves the biochemical characteristics of oral fluid in patients with chronic generalized periodontitis associated with osteopenia and osteoporosis.
Keywords:
chronic generalised periodontitis osteopenia osteoporosis calcium phosphorus dental treatment therapeutic and prophylactic complex
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Publication:
«World of Medicine and Biology» Vol. 22 No. 1 (2026) , с. 56-60
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