MANAGEMENT OF REPRODUCTIVE SYSTEM DISORDERS IN ADOLESCENT FEMALES WITH CONGENITAL FEMALE GENITAL TRACT ANOMALIES

Authors:

Abstract:

Congenital female genital tract anomalies in adolescent females represent a substantial component among the factors contributing to compromised reproductive health. Determining the prevalence of female genital tract anomalies in adolescents and developing strategies to manage associated reproductive disorders via hormonal profiling remain cornerstone objectives in modern pediatric and adolescent gynecology. To evaluate the functional characteristics of the reproductive system, we examined 54 adolescent females with female genital tract anomalies aged 10 to 20 years during the pre-pubertal and pubertal periods. For hormonal profile comparison, 20 age-matched healthy controls were evaluated. All patients underwent clinical assessment in accordance with the protocols of the Ministry of Health of Ukraine. Within the female genital tract anomalies cohort, a significant proportion comprised patients with vaginal and uterine atresia (12 cases, 22.2 %) and complete uterus didelphys with a double vagina (4 cases, 7.4 %). A transverse vaginal septum was identified in 5 patients (9.3 %), and a transverse septum coexisting with a bicornuate uterus was recorded in 2 cases (3.7 %). Among the cohort, the prevalence of a partial uterine septum was 29.6 % (16 cases), while a complete uterine septum was documented in 12.9 % (7 cases). A bicornuate uterus was detected in 3 girls (5.6 %), and an uncornuate uterus was found in 1 patient (1.9 %). Hymenal atresia (imperforate hymen) was diagnosed in 4 cases (7.4 %). Compared to healthy controls, patients with female genital tract anomalies demonstrated menstrual cycle irregularities and hormonal imbalances. To establish the prevalence of these disorders, routine clinical medical check-ups were conducted, incorporating standardized screening, pelvic ultrasonography, and magnetic resonance imaging. The choice of therapeutic strategy is dictated by the specific type of female genital tract anomalies and its associated menstrual dysfunction stemming from hypothalamic-pituitary-ovarian axis impairment. Surgical intervention is not universally warranted in all cases, being strictly reserved for severe structural and obstructive malformations.

Keywords:

female genital tract anomalies reproductive health management of reproductive disorders in adolescent females menstrual dysfunction hormonal profile assessment

References:

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Publication:

«World of Medicine and Biology» Vol. 22 No. 96 (2026) , с. 66-70
УДК 618.1-007.1-02:[616:612.6]-08-036.82

DOI:

https://doi.org/10.26724/2079-8334-2026-2-96-66-70