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IMPACT OF ELECTRONIC CIGARETTES ON ENDOTHELIAL FUNCTION AND CARDIOPULMONARY HEALTH IN YOUNG ADULTS

Published 2026-06-30

Authors:

Sadigova T.A.
Azerbaijan Medical University image/svg+xml
https://orcid.org/0000-0003-0608-8384
Valikhan T.
Azerbaijan Medical University image/svg+xml
https://orcid.org/0009-0008-1441-9247
Abstract:
The global use of electronic cigarettes has increased rapidly, particularly among adolescents and young adults, driven by aggressive marketing, flavored products and misconceptions about relative safety. Electronic cigarette aerosols contain nicotine, propylene glycol, glycerol, flavoring chemicals, carbonyl compounds, volatile organic compounds, heavy metals and other toxicants. Current evidence indicates that vaping induces oxidative stress, endothelial dysfunction, immune dysregulation and structural injury of the respiratory tract. Clinically, electronic cigarette use is associated with electronic cigarette or vaping product use-associated lung injury, worsening of asthma, decreased lung function and adverse cardiovascular effects, including acute blood pressure and heart rate elevation, impaired flow-mediated dilation and activation of pro-thrombotic pathways. In adolescents, additional concerns relate to neurocognitive development and nicotine dependence. This narrative review summarizes contemporary data on the pulmonary, cardiovascular and immunological effects of electronic cigarettes, compares them with combustible tobacco, highlights gaps in long-term evidence and identifies the need for prospective studies of endothelial and lung injury biomarkers in young users.
Keywords:
electronic cigarettes vaping endothelial dysfunction cardiovascular disease lung injury adolescents
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Publication:
«World of Medicine and Biology» Vol. 22 No. 96 (2026) , с. 243-247
УДК 613.84:616.12/.24-053.7
DOI:
https://doi.org/10.26724/2079-8334-2026-2-96-243-247