EARLY PREGNANCY FOLLOWING HYSTEROSCOPIC MANAGEMENT OF COMPLETE HYDATIDIFORM MOLE
Clinical Case

EARLY PREGNANCY FOLLOWING HYSTEROSCOPIC MANAGEMENT OF COMPLETE HYDATIDIFORM MOLE

Published 2026-06-30

Authors:

Aliyeva R.M.
State Security Service Military Hospital, Baku
https://orcid.org/0000-0001-9661-8080
Safarova S.I.
Azerbaijan Medical University image/svg+xml
https://orcid.org/0000-0003-4663-5557
Karimova S.N.
Azerbaijan Medical University image/svg+xml
https://orcid.org/0009-0001-7569-0152
Shahmaliyeva U.R.
Scientific Research Institute of Obstetrics and Gynecology
https://orcid.org/0000-0001-8436-1935
Alizade G.A.
Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev image/svg+xml
https://orcid.org/0009-0002-8082-4044

Abstract:
Complete hydatidiform mole is a form of gestational trophoblastic disease requiring timely diagnosis, complete uterine evacuation, and careful postoperative monitoring of beta-human chorionic gonadotropin levels. This article presents a clinical case of a 22-year-old primigravida who presented at 8 weeks of amenorrhea with vaginal bleeding. Transvaginal ultrasound revealed a heterogeneous intrauterine structure with cystic spaces, while serum beta-human chorionic gonadotropin was markedly elevated. The patient underwent hysteroscopy-assisted evacuation under general anesthesia using controlled intrauterine pressure, aspiration with a Karmen cannula, and mechanical removal of residual chorionic villi under direct visualization. The procedure was completed without complications, with minimal blood loss and rapid postoperative recovery. Histopathological examination confirmed complete hydatidiform mole. Although beta-human chorionic gonadotropin initially decreased, subsequent elevation raised suspicion of persistent gestational trophoblastic disease. Further evaluation and repeat curettage demonstrated progesterone-related endometrial changes, suggesting early new pregnancy rather than residual molar tissue. This case highlights the diagnostic value of hysteroscopy, the importance of beta-human chorionic gonadotropin surveillance, and the need for early contraceptive counseling after molar evacuation.
Keywords:
hydatidiform mole hysteroscopy β-hCG pregnancy trophoblastic disease
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Publication:
«World of Medicine and Biology» Vol. 22 No. 96 (2026) , с. 272-276
УДК 618.36-006.04-07-08