ANALYSIS OF CHANGES IN THE MINERALIZATION INDEX IN THE ORAL FLUID OF CHILDREN WITH FLUOROSIS DURING COMPREHENSIVE ORTHODONTIC TREATMENT

Authors:

Abstract:

This study assessed acid and alkaline phosphatase activities and the mineralisation index in oral fluid during orthodontic treatment in children with endemic fluorosis. Twenty-five children aged 6–7 years were examined: the main group (n=13) received a therapeutic and preventive complex alongside dental treatment and professional oral hygiene; the comparison group (n=12) received standard measures. Measurements were obtained at baseline, before bracket placement, and at 1, 6 and 12 months. At one year, acid phosphatase activity in the main group decreased by 56.3 %, while mean alkaline phosphatase activity increased by 78.0 % from baseline. The mineralisation index increased from 0.94 to 3.86 arbitrary units, whereas the comparison-group value was 0.79. Comprehensive supportive care was associated with favourable enzymatic trajectories; their clinical significance requires further confirmation.

Keywords:

dental fluorosis children oral fluid acid phosphatase alkaline phosphatase mineralisation index orthodontic treatment

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Publication:

«World of Medicine and Biology» Vol. 22 No. 97 (2026), pp. 166-171
UDC [616-053.5+616-003.663.4]:616.31-08-039.71

DOI:

https://doi.org/10.26724/2079-8334-2026-3-97-166-171