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Clinical Case

ACUTE KIDNEY INJURY OF THE HUS-LIKE SYNDROME TYPE ON THE BACKGROUND OF SARS-COV-2 IN CHILDREN

Published 2026-09-30

Authors:

Pypa L.V.
National Pirogov Memorial Medical University, Vinnytsya image/svg+xml
https://orcid.org/0000-0002-4448-5308
Dudikova L.V.
Kharkiv National University of Internal Affairs image/svg+xml
https://orcid.org/0000-0002-5841-0147
Lysytsia Yu.M.
National Pirogov Memorial Medical University, Vinnytsya image/svg+xml
https://orcid.org/0000-0003-0248-0338
Romanchuk K.Yu.
National Pirogov Memorial Medical University, Vinnytsya image/svg+xml
https://orcid.org/0009-0005-1565-5610
Krenov K.Yu.
National Pirogov Memorial Medical University, Vinnytsya image/svg+xml
https://orcid.org/0000-0003-0654-9726
Ruda V.I.
National Pirogov Memorial Medical University, Vinnytsya image/svg+xml
https://orcid.org/0000-0002-3736-3572
Odarchuk I.V.
National Pirogov Memorial Medical University, Vinnytsya image/svg+xml
https://orcid.org/0000-0002-6484-1525
Abstract:
Since the beginning of the pandemic, SARS-CoV-2 has mutated into different variants. In 2025, new sublines of the Omicron variant appeared – “Stratus” and “Nimbus”, which are characterized by the ability to evade existing population immunity. Clinical course with predominant damage to the upper respiratory tract, gastrointestinal tract, nervous system, acute kidney injury. Objective: to analyze the course of COVID-19 coronavirus infection in children, complicated by kidney damage in the form of hemolytic-uremic syndrome. Two clinical cases of hemolytic-uremic syndrome in children with COVID-19 coronavirus infection (subvariants Omicron, 2025) are presented. Conclusions: a feature of the course of COVID-19 was kidney damage in the absence of clinically pronounced respiratory syndrome and with relatively prolonged viremia. Kidney damage occurred in the form of hemolytic-uremic syndrome with the presence of hemolytic anemia in combination with thrombocytopenia and the development of acute renal failure.
Keywords:
coronavirus infection hemolytic uremic syndrome respiratory failure multisystem inflammatory syndrome thrombotic thrombocytopenic microangiopathy complement-associated atypical hemolytic uremic syndrome
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Publication:
«World of Medicine and Biology» Vol. 22 No. 97 (2026), pp. 272-277
UDC 616.831-009.863
DOI:
https://doi.org/10.26724/2079-8334-2026-3-97-272-277