NEUROLOGICAL MANIFESTATIONS IN HIV-POSITIVE INMATES WITHIN AZERBAIJANI CORRECTIONAL FACILITIES
Clinical medicine

NEUROLOGICAL MANIFESTATIONS IN HIV-POSITIVE INMATES WITHIN AZERBAIJANI CORRECTIONAL FACILITIES

Published 2025-11-27

Authors:

N.R. Abdullayeva

Abstract:
A cross-sectional study recruited 376 incarcerated individuals from Azerbaijani penitentiary institutions, including 257 human immune deficiency virus (HIV)-positive (main group) and 119 HIV-negative participants (control group). Clinical, neurological, and psychological evaluations were conducted using standardized tools, adapted for the local context. The main group had shorter sentences, with 36.6 % serving ≤1 year, (14.3 % in the control group (p<0.001)), and a higher proportion with only secondary education (77.0 % vs. 42.9 %, p<0.001), higher rates of infectious diseases, and 64.6 % with drug addiction (vs. 5.9 %, p<0.001). Cognitive impairments and neurological disorders, including dementia, were more prevalent in the main group, with 41.3 % showing any dementia (vs. 21.0 % in the control group, p<0.001). Quality-of-life assessments showed lower scores in the main group. HIV-infected prisoners experience significantly worse cognitive function, higher rates of infectious and psychological comorbidities, and a lower quality of life compared to non-infected inmates.
Keywords:
HIV polyneuropathy HIV-associated neurocognitive disorder quality of life
References:
  1. Altice FL, Azbel L, Stone J, Brooks-Pollock E, Smyrnov P, Dvoriak S, et al. The perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia. The Lancet, 2016; 388(10050), 1228-1248. https://doi.org/10.1016/S0140-6736(16)30856-X.
  2. Azbel L, Polonsky M, Wegman MP, Bachireddy C, Meyer JP, Sereda Y, et al. Drug injection, sexual risk, and HIV prevalence among incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine. J Infect Dev Ctries. 2018;12(8):620–9. doi:10.3855/jidc.1011.
  3. Culbert GJ, Bazazi AR, Waluyo A, Murni A, Muchransyah AP, Irawan A, et al. Integrated treatment of HIV and opioid use disorder in prisons: a systematic review and meta-analysis. Lancet HIV. 2023;10(2):e91–102. doi:10.1016/S2352-3018(23)00002-4.
  4. Davlidova S, Haley-Johnson Z, Nyhan K, Farooq A, Vermund SH, Ali S. Prevalence of HIV, HCV and HBV in Central Asia and the Caucasus: A systematic review. International Journal of Infectious Diseases. 2021; 104, 510–525. doi:10.1016/j.ijid.2020.12.068.
  5. Fazel S, Bromberg DJ, Altice FL. HIV, substance use, and mental health care in prisons. Lancet Psychiatry. 2022 Sep;9(9):694-695. doi: 10.1016/S2215-0366(22)00243-7. Epub 2022 Jul 14. PMID: 35843228; PMCID: PMC9827418.
  6. Golrokhi R, Farhoudi B, Taj L, Pahlaviani FG, Mazaheri-Tehrani E, Cossarizza A, et al. HIV Prevalence and Correlations in Prisons in Different Regions of the World: A Review Article. Open AIDS J. 2018 Aug 31;12:81-92. doi: 10.2174/1874613601812010081.
  7. Kelebie MA, Tinsae T, Alemayehu BF, Walelign GK, Takelle GM. Prevalence and associated factors of neurocognitive disorder among people living with HIV/AIDS in the South Gondar zone primary hospitals, North-West Ethiopia: an institution-based cross-sectional study. BMJ Open. 2024 May 2;14(5):e082773. doi: 10.1136/bmjopen-2023-082773.
  8. Lier AJ, Tarfa A, Shenoi SV, Kuo I, Springer SA. HIV and Substance Use Disorders. Infect Dis Clin North Am. 2024 Sep;38(3):599-611. doi: 10.1016/j.idc.2024.06.003.
  9. Mehdiyev R, Alikhanova N, Gurbanova E. HIV/tuberculosis/hepatitis C virus services for incarcerated populations in Azerbaijan and the Eastern Europe Central Asia region. Curr Opin HIV AIDS. 2019 Jan;14(1):66-70. doi: 10.1097/COH.0000000000000513.
  10. Mykytenko AO, Akimov O Ye, Yeroshenko GA, Neporada KS. Morphological and functional changes of the hepatic vascular bed under the conditions of modeling alcoholic hepatitis. World of medicine and biology. 2021; 3 (77): 229–236. DOI: DOI 10.26724/2079-8334-2021-3-77-229-236.
  11. Polonsky M, Azbel L, Wegman MP, Izenberg JM, Bachireddy C, Martoma J, et al. Pre-incarceration HIV transmission risk behaviors among soon-to-be released prisoners and associated risk factors during community re-entry in Azerbaijan, Kyrgyzstan and Ukraine. AIDS Behav. 2016;20(5):1075–85. doi:10.1007/s10461-015-1216-3.
  12. Ranjit YS, Azbel L, Krishnan A, Altice FL, Meyer JP. Evaluation of HIV risk and outcomes in a nationally representative sample of incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine. AIDS Care. 2019 Jul;31(7):793-797. doi: 10.1080/09540121.2019.1573969.
  13. State Statistical Committee of the Republic of Azerbaijan. Statistical yearbook: Health and social protection. Baku: State Statistical Committee. 2022. Available at: https://www.stat.gov.az/?lang=en.
  14. United Nations Office on Drugs and Crime (UNODC). HIV prevention, treatment, care and support in prison settings: A framework for an effective national response. 2021. Retrieved from https://www.unodc.org/unodc/en/hiv-aids/publications.html.
  15. WHO.Global HIV, Hepatitis and STIs Programmes. People in prisons and other closed settings. 2020. Available at: https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/populations/people-in-prisons.
Publication:
«World of Medicine and Biology» Vol. 21 No. 94 (2025) , с. 7-11
УДК 616.8:616.98:578.828.6