TREATMENT OUTCOMES FOR NEWBORNS WITH CONGENITAL DIAPHRAGMATIC HERNIA

Authors:

Abstract:

The purpose of the study was to assess the results of surgical treatment of newborns with congenital diaphragmatic hernia based on a set of clinical, cardiological and quality of life indicators. The study included 70 newborns diagnosed with congenital diaphragmatic hernia. Depending on the method of surgical intervention, the children were divided into 2 groups. The comparison group consisted of 44 newborns operated on using the traditional open method, and the main group consisted of 26 newborns operated on using a new minimally invasive surgical technique – endosurgery. The study showed that the method of surgical intervention proposed by us allows to reduce the length of stay in the clinic, quickly improve the condition of children, and return quality of life indicators to normal.

Keywords:

congenital diaphragmatic hernia newborns surgery quality of life clinic

References:

1. Aljuhani A, Alsumaili AA, Alyaseen EM, Daak LI, Esmail A, Alzohari JE, et al. Minimally Invasive Approach Versus Traditional Approach for Treating Congenital Diaphragmatic Hernia: A Systematic Review and Meta-Analysis. Cureus. 2025 Jan 17;17(1):e77596. doi: 10.7759/cureus.
2. Baschat AA, Desiraju S, Bernier ML, Kunisaki SM, Miller JL. Management advances for congenital diaphragmatic hernia: integrating prenatal and postnatal perspectives. Transl Pediatr. 2024;13(4):643-662. doi: 10.21037/tp-23-602.
3. Brandt JB, Werther T, Groth E, Küng E, Golej J, Berger A. Risk factors for mortality in infants with congenital diaphragmatic hernia: a single center experience. Wien Klin Wochenschr. 2021;133,674–679. https://doi.org/10.1007/s00508-021-01843-w.
4. Burgos CM, Perrone EE, Zahn K, Hedrick HL, Challenges and Controversies in the Surgical Management of Congenital Diaphragmatic Hernia, Seminars in Fetal and Neonatal Medicine. 2025;101648, https://doi.org/10.1016/j.siny.2025.101648.
5. Chen KK, Edwards MJ. Delayed presentation of a right congenital diaphragmatic hernia following left congenital diaphragmatic hernia repair in infancy. International Journal of Surgery Case Reports. 2023;Volume 105, 108020, https://doi.org/10.1016/j.ijscr.2023.108020.
6. Heiwegen K, van Rooij IALM, van Heijst A, Blaauw I, Botden SMBI. Surgical Complications in Children with CDH: A Multivariate Analysis. World Journal of Surgery. 2020;44,2042–2048. https://doi.org/10.1007/s00268-020-05387-4.
7. Hemanth RR, Rajan Y, Potluri V. Congenital Right Diaphragmatic Hernia Presenting in Adult Life: A Rare Case. Cureus. 2022;14(11): e31168. doi:10.7759/cureus.31168.
8. Jank M, Boettcher M, Keijzer R. Surgical management of the diaphragmatic defect in congenital diaphragmatic hernia: a contemporary review. World J Pediatr Surg. 2024;21,7(3):e000747. doi: 10.1136/wjps-2023-000747.
9. Klinke M, Martel R, Weiß C. Thoracoscopic hiatoplasty in congenital diaphragmatic hernia is safe and less invasive: a prospective propensity-matched short-term study. Pediatr Surg Int. 2025;41,318. https://doi.org/10.1007/s00383-025-06218-0.
10. Perveen S, Frigeni M, Benveniste H, Kurepa D Cellular, molecular, and metabolic aspects of developing lungs in congenital diaphragmatic hernia. Front. Pediatr. 2022;10:932463. doi: 10.3389/fped.2022.932463.
11. Politis MD, Bermejo-Sánchez E, Canfield Mark A, Contiero P, Janet D. Prevalence and mortality in children with congenital diaphragmatic hernia: a multicountry study, Annals of Epidemiology. 2021; 56: 61-69.e3, https://doi.org/10.1016/j.annepidem.2020.11.007.
12. Ruano R, Takashi E, Da Silva MM, Campos JA, Tannuri U, Zugaib M. Prediction and probability of neonatal outcome in isolated congenital diaphragmatic hernia using multiple ultrasound parameters. Ultrasound Obstet Gynecol. 2012;39(1):42–9. https://doi.org/10.1002/uog.10095.
13. Tantu T, Tantu T, Hailu Y, Gashaw D, Melkamu B. Prevalence and factors associated with low 5th minute APGAR score among mothers who birth through emergency cesarean section: prospective cross-sectional study in Ethiopia. BMC Pregnancy Childbirth. 2025;25(1):342. doi: 10.1186/s12884-025-07456-9.
14. Toyoshima K, Aoki H, Katsumata K, Sato Y, Inoue H, Ito M et al. Japanese Congenital Diaphragmatic Hernia Study Group. Isolated congenital diaphragmatic hernia and three-year neurodevelopmental outcomes. Pediatr Res. 2025;98(2):690-696. doi: 10.1038/s41390-025-03870-z.

Publication:

«World of Medicine and Biology» Vol. 21 No. 94 (2025) , с. 51-54
УДК 616.26 – 008.13 – 053.33– 10

DOI:

https://doi.org/10.26724/2079-8334-2025-4-94-51-54