ASSESSMENT OF THE PEROXIDE OXIDATION INDEX OF LIPIDS IN THE ORAL FLUID OF CHILDREN WITH FLUOROSIS IN THE DYNAMICS OF COMPREHENSIVE ORTHODONTIC TREATMENT

Authors:

Abstract:

The study was devoted to the effect of a treatment and preventive complex of drugs on the content of malondialdehyde in the oral fluid of children with endemic fluorosis and orthodontic pathology Twenty-five children (6–7 years old) were allocated to a comparison group and a main group. Unstimulated whole saliva was collected at baseline, after one month (pre-bonding), and at 3, 6, and 12 months after bracket placement. Salivary malondialdehyde concentrations were measured spectrophotometrically. Findings indicate that the treatment and preventive complex exerts sustained antioxidative and membrane-protective effects, counteracting the combined oxidative burden of fluorosis and orthodontic pathology.

Keywords:

dental fluorosis malondialdehyde lipid peroxidation orthodontic treatment antioxidants children therapeutic-prophylactic complex

References:

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Publication:

«World of Medicine and Biology» Vol. 21 No. 94 (2025) , с. 140-144
УДК [616-053.5+616-003.663.4]:616.31-08-039.71

DOI:

https://doi.org/10.26724/2079-8334-2025-4-94-140-144