TRANSFORMATION OF PRIMARY DISABILITY INDICATORS DUE TO EPILEPSY UNDER MARTIAL LAW
Огляди літератури

TRANSFORMATION OF PRIMARY DISABILITY INDICATORS DUE TO EPILEPSY UNDER MARTIAL LAW

Published 2025-04-16

Authors:

V.M. Kornatsky
A.G. Kyrychenko
N.A. Sanina
S.V. Abramov
I.V. Rozhkova
E.V. Begun

Abstract:
The problem of disability remains painful for all countries of the world, both from a medical and socio-economic point of view. Diseases of the nervous system, especially epilepsy in people of working age, are a significant problem in Ukraine. The ongoing war is expected to exacerbate this problem. The study aimed to analyze trends in disability due to epilepsy in wartime settings to identify causal patterns of disability. In this article, disability due to epilepsy is considered one of the essential medical and social characteristics of public health in wartime. The relevance of this problem in our country is due to its significant scale and negative dynamics, especially at the expense of working-age people.
Keywords:
epilepsy primary disability working and adult population military status
References:
  1. Kyrychenko AG, Sanina NA, Abramov SV, Perepelichna RY, Khanyukova IY, Domansky AM, et al. Disability in Ukraine: yesterday, today, tomorrow: Kyiv: 2023. 196 s. [in Ukrainian].
  2. Ageing Europe – statistics on health and disability Disability levels and trends among older adults in Europe based on the 3-category GALI and SHARE data 2020.
  3. Al-Makhamreh H, Alkhulaifat D, Al-Ani A, Mafrachi B, Saadeh A, Al-Ani H, et al. The impact of War-related stress on coronary artery Disease Severity in War survivors: a SYNTAX study. Int J Environ Res Public Health. 2021:18(6):3233. doi.org/10.3390/ijerph18063233.
  4. Balestrini S, Arzimanoglou A, Blümcke I, Scheffer IE, Wiebe S, Zelano J. The aetiologies of epilepsy. Epileptic Disorders. 2021. 23 (1): 1–16. doi.org/10.1684/epd.2021.1255.
  5. Beghi E. The epidemiology of epilepsy. Neuroepidemiology. 2020; 54 (2): 185–191. doi.org/10.1159/000503831.
  6. Beniczky S, Trinka E, Wirrell E, Abdulla F, Al Baradie R, Alonso Vanegas M, et al. Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy. Epilepsia. First published: 2025: 66(6). 1804–1823. doi: 10.1111/epi.18338.
  7. Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, et al. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022; 24:447–95. doi.org/10.1684/epd.2022.1430.
  8. Centers for Disease Control and Prevention. CDC Activities Related to Recommendations of the 2012 IOM Report, Epilepsy Across the Spectrum, 2012–2022: Final Progress Report. US Dept of Health and Human Services; 2022.
  9. Contreras Ramirez V, Patedakis Litvinov B, Gunawardane NA, Zhao CW, Yotter C, Quraishi IH, et al. Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing. Epileptic Disord. 2022; 24:899–905. doi.org/10.1684/epd.2022.1472.
  10. Fischer D, Edlow BL. Coma prognostication after acute brain injury. JAMA Neurol. 2024; 81(4): 405. doi.org/10.1001/ jamaneurol.2023.5634.
  11. Ellis CA, Petrovski S, Berkovic SF. Epilepsy genetics: clinical impacts and biological insights. Lancet Neurol. 2020. 19 (1): 29–30. doi: 10.1016/S1474-4422(19)30269-8.
  12. Garbuz DG, Davletshin AА, Litvinova SA, Fedotova IB, Surina NM, Poletaeva II, et al. Rodent models of audiogenic epilepsy: genetic aspects, advantages, current problems and perspectives. Biomedicines. 2022; 10 (11): 2934. doi:org/10.3390/biomedicines10112934.
  13. Hanif S., Musick S.T. Reflex epilepsy. Aging Dis. 2021; 12 (4): 1010-20. doi.org/10.14336/AD.2021.0216.
  14. Hirsch E, French J, Scheffer IE, Bogacz A, Alsaadi T, Sperling MR, et al. ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022; 63 (6): 1475–99. doi.org/10.1111/epi.17236.
  15. Irizarry R, Sukato D, Kollmar R. Schild S, Silverman J, Sundaram K, et al. Seizures induce obstructive apnea in DBA/2J audiogenic seizure-prone mice: lifesaving impact of tracheal implants. Epilepsia. 2020; 61 (2): 13–16. doi.org/10.1111/epi.16431.
  16. Khoo A, Alim-Marvasti A, de Tisi J, Diehl B, Walker MC, Miserocchi A, et al. Value of semiology in predicting epileptogenic zone and surgical outcome following frontal lobe epilepsy surgery. Seizure. 2023; 106 :29–35. doi.org/10.1016/j. seizure.2023.01.019.
  17. Leonardi M, Martelletti P, Burstein R, Fornari A, Grazzi L, Guekht A, et al. The World Health Organization Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders and the headache revolution: from headache burden to a global action plan for headache disorders. J Headache Pain, 2024;25(1):4. doi: 10.1186/s10194-023-01700-3.
  18. Mental health atlas 2020. Geneva: World Health Organization. Licence: CC BY-NC-SA 3.0 IGO. 2021.
  19. Mukherjee S, Arisi GM, Mims K, Hollingsworth G, O'Neil K, Shapiro LA, et al. Neuroinflammatory mechanisms of post-traumatic epilepsy. J Neuroinflammation. 2020; 17 (1):193. doi.org/10.1186/s12974-020-01854-w.
  20. Perucca P, Bahlo M, Berkovic SF. The genetics of epilepsy. Annu Rev Genomics Hum Genet. 2020; 21: 205–230. doi.org/10.1146/annurev-genom-120219-074937.
  21. Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, et al. The ILAE classification of seizures and the epilepsies: modification for seizures in the neonate. Epilepsia. 2021;62:615–28. doi.org/10.1111/epi.16815.
  22. Ramirez VC, Vaddiparti A, Blumenfeld H. Testing awareness in focal seizures: Clinical practice and interpretation of current guidelines. Ann Clin Transl Neurol. 2022; 9(5). 762–765. doi.org/10.1002/acn3.51552.
  23. Reddy C, Saini AG. Metabolic epilepsy. Indian J Pediatr. 2021; 88 (10): 1025-1032. doi.org/10.1007/s12098-020-03510-w.
  24. Riney K, Bogacz A, Somerville E, Hirsch E, Nabbout R, Scheffer IE, et al. International League Against Epilepsy classification and definition of epilepsy syndromes with onset at a variable age: position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022; 63 (6): 1443–74. doi.org/10.1111/epi.17240.
  25. Romanello M, di Napoli C, Green C, Kennard H, Lampard P, Scamman D, et al. The 2023 report of the Lancet Countdown on health and climate change: the imperative for a health-centred response in a world facing irreversible harm. Lancet 2023; 402: 2346–2394. doi: 10.1016/S0140-6736(23)01859-7.
  26. Specchio N, Wirrell EC, Scheffer IE, Nabbout R, Riney K, Samia P, et al. International league against epilepsy classification and definition of epilepsy syndromes with onset in childhood: position paper by the ILAE task force on nosology and definitions. Epilepsia. 2022; 63(6): 1398–442. doi.org/10.1111/epi.17241.
  27. Vlachou M, Ryvlin P, Armand Larsen S, Beniczky S. Focal electroclinical features in generalized tonic–clonic seizures: Decision flowchart for a diagnostic challenge. Epilepsia. 2024; 65(3): 725–38. doi.org/10.1111/epi.17895.
  28. Walsh S, Merrick R, Brayne C. The relevance of social and commercial determinants for neurological health. Anniversary Lecture. 2022: 21(12), 1151–1160. doi.org/10.1016/S1474-4422(22)00428-8.
  29. Wirrell EC, Nabbout R, Scheffer IE, Alsaadi T, Bogacz A, French JA, et al. Methodology for classification and definition of epilepsy syndromes with list of syndromes: report of the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022; 63 (6): 1333–48. doi.org/10.1111/epi.17237.
  30. World Health Organization. Intersectoral global action plan on epilepsy and other neurological disorders 2022–2031. Geneva: World Health Organization; 2023. Licence: CC BY-NC-SA 3.0 IGO.
Publication:
«World of Medicine and Biology» Vol. 21 No. 92 (2025) , с. 231-239
УДК 615.322035:615.89