PREVENTION OF PLACENTAL DYSFUNCTION IN PREGNANT WOMEN WITH DENTAL PATHOLOGY

Authors:

Abstract:

In pregnant women, due to changes in the microbiota, diet, and insufficient oral hygiene, the level of inflammatory markers increases, which can contribute to the dysfunction of the fetoplacental complex. The aim of the study was to assess the impact of dental pathology in pregnant women on the risk of placental dysfunction. We studied 87 pregnant women, including 57 women with pathology of hard tooth tissues and periodontal tissues and 30 pregnant women without signs of dental pathology. The microbiocenosis of the oral cavity, indicators of hormonal, biochemical and biophysical profile, morphological changes in the placenta were studied. A positive correlation between the indicators of oral infection and periodontal pathology (r=0.58–0.63, p<0.05), as well as the relationship between the increase in C-reactive protein and the increase in periodontal pathology indices (r=0.58–0.63, p<0.05) was determined. The presence of chronic oral infection was accompanied by a decrease in the content of hormones of the fetoplacental complex, deterioration of the biophysical profile of the fetus and uteroplacental-fetal blood flow, development of hemodynamic and involutional-dystrophic disorders of the placenta, birth of low-birth-weight children, which confirms the importance of providing timely dental care to prevent placental dysfunction and perinatal complications.

Keywords:

pregnancy placenta periodontium caries gingivitis fetoplacental complex placental dysfunction

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Publication:

«World of Medicine and Biology» Vol. 20 No. 89 (2024) , с. 153-158
УДК 616 .36-008-084

DOI:

https://doi.org/10.26724/2079-8334-2024-3-89-153-158