Article
THE INFLUENCE OF PALEOCEREBELLAR CORTEX ASPIRATION UPON FORMATION OF EPILEPTIC FOCI IN BRAIN CORTEX OF RATS WITH RESISTANT FORM OF EPILEPTIC SYNDROME
About the author: | Polyzsny V.A. |
Heading | EXPERIMENTAL MEDICINE |
Type of article | Научная статья |
Annotation | In acute experiments on male Wistar rats on the model of resistant form of epileptic syndrome, which was induced in the course of three weeks corazol administration (30,0 mg/kg, i.p.) fiollowed by four weeks free from epileptogen administrations, it was established that paleocerebellar cortex aspiration shortened the time of epileptic discharges appearance, which were induced in frontal cortex by applications of penicillin sodium salt solution (10.000 IU/ml). Besides, the shortening of the time of gaining maximal magnitude of discharges was established along with increasing their amplitude and shifting of the mode of interspike intervals to the side of their shortening. The aspiration of paleocerebellar cortex increased the time of existence of epileptic foci. |
Tags | epileptic focus, paleocerebellar cortex, penicillin, resistant form of peileptic syndrome |
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Publication of the article | «World of Medicine and Biology» №3(30), 2011 year, 21-24 pages, index UDK 616.831.31-009.24- 092.9 |