| About the author: |
Falalyeyeva T.M. |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Научная статья |
| Annotation |
The influence of prolonged administration of monosodium glutamate (MSG) on body weight in rats was studied. Found that 10 -, 20 -, 30-days feeding by MSG in doses 15 to 30 mg/kg (equivalent to 1 and 2 g/person) leads to increased of body weight. It is concluded that prolonged, excessive and systemic use of MSG causes obesity. Secondly, the maximum dose of MSG should be reconsidered taking into account its influence on body weight. |
| Tags |
Monosodium glutamate, obesity |
| Bibliography |
- Гланс С. Медико-биологическая статистика / С. Гланс – Москва, Практика, 1999. – 459 с.
- Мальцев В.И. Этическая оценка методик проведения исследований / Мальцев В.И., Белоусов Д.Ю. // Еженед. Аптека. – 2001. - № 34. - С. 35.
- МОЗ, Центр медичної статистики МОЗ України. Київ, 2009. – 105 С.
- Bui A. L. Epidemiology and risk profile of heart failure / A.L. Bui, T.B. Horwich, G.C. Fonarow // Nat. Rev. Cardiol. – 2010. – Vol. 9. – P. 23-27.
- Butte N. F. Impact of infant feeding practices on childhood obesity/ N. F. Butte // J Nutr. – 2009. – Vol. 139. – N 2. – P. 412-416.
- Ceska R. Comprehensive management of cardiovascular risk. Focusing on telmisartan / R. Ceska, S. Krutská, L. Zlatohlávek [et al.] // Vnitr. Lek. – 2010. – Vol. 56. – N 8. – P. 839-844.
- Collison K. S. Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile / K. S. Collison // Br. J Nutr. – 2011. – Vol. 24. – P. 1-10.
- Dawson R. Attenuation of leptin-mediated effects by monosodium glutamate-induced arcuate nucleus damage / R. Dawson, M.A. Pelleymounter [et al.] // Am. J Physiol. – 1997. – Vol. 273. – P. 202-206.
- Gallagher E. J. Insulin, insulin resistance, obesity, and cancer / E.J. Gallagher, D. LeRoith // Curr. Diab. Rep. – 2010. – Vol. 10. – P. 93-100.
- He K. Association of monosodium glutamate intake with overweight in Chinese adults: the INTERMAP Study / K. He, L. Zhao, M. L. Daviglus [et al.] // Obesity. - 2008. – Vol. 16. - № 8. – P. 1875–1880.
- Jokiel M. Breast cancer risk factors - possibilities of primary prevention / M. Jokiel // Przegl. Epidemiol. – 2010. – Vol. 64. – N 3. – P. 435-438.
- Livingstone B. Epidemiology of childhood obesity in Europe / B. Livingstone// Eur J Pediatr.– 2000.– Vol.159. - N 1. – P. 14-34.
- Lorden J. F. Behavioral and endocrinological effects of single injections of monosodium glutamate in the mouse / J. F. Lorden, A. Caudle // Neurobehav. Toxicol. Teratol. – 1986. – Vol. 8. - №5. – P. 509-519.
- Luz J. Effect of food restriction on energy expenditure of monosodium glutamate-induced obese rats / J. Luz, V. P. Pasin, D. J. Silva [et al.] // Nutr. Metab. – 2010. – Vol. 56. - № 1. – P. 31-35.
- Samuels A. Monosodium glutamate is not associated with obesity or a greater prevalence of weight gain over 5 years: findings from the Jiangsu Nutrition Study of Chinese adults - comments by Samuels. / A. Samuels // Br. J Nutr. – 2010. – Vol. 9. – P. 11-13.
- Skouby S.O. Hormonal contraception in obesity, the metabolic syndrome, and diabetes / S.O. Skouby // Ann N Y Acad. Sci. – 2010. – Vol. 1205. – P. 240-244.
- Stothard K. J. Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis / K. J. Stothard, P. W. Tennant, R. Bell [et al.] // JAMA. – 2009. – Vol. 301. – N 6. – P. 636-650.
- Tarasoff L. Monosodium L-glutamate: A double-blind study and review / L. Tarasoff, M. F. Kelly // Food and Chemical Toxicol. - 1993. – Vol. 31. – P. 1019–1035.
- Wing S. S. The UPS in diabetes and obesity / S. S. Wing // BMC Biochem. – 2008. – Vol. 21. – N. 9. - P. 6- 12.
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| Publication of the article |
«World of Medicine and Biology» №2(33), 2012 year, 170-172 pages, index UDK 577.112.384 |
