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    Delva M., Lytvynenko N.

    PECULIARITIES OF POSTISCHEMIC INFLAMMATORY RESPONSE AT ACUTE LACUNAR STROKES IN ABDOMINALLY OBESE PATIENTS


    About the author: Delva M., Lytvynenko N.
    Heading CLINICAL MEDICINE
    Type of article Научная статья
    Annotation Studied the serum levels of the inflammatory interleukins, C-reactive protein, monocyte hemoattractant protein-1 in the 1st and 10th days after lacunar strokes in patients with normal body weight and with abdominal obesity class II. Abdominally obese patients, in comparison with normal body weight patients, have enhanced postischemic inflammatory response during acute lacunar strokes – significant serum increase of C-reactive protein (21,7±5,2 mg/l vs. 7,1±1,4 mg/l, p <0.05), tumor necrosis factor-α (19,0±4,3 pg/ml vs. 8,0±2,0 pg/ml, p <0.05), interleukin-1β (3,0±1,0 pg/ml vs. 0,5±0,3 pg/ml, p<0.05), interleukin-6 (14,3±3,4 pg/ml vs 5,5±1,1 pg/ml, p<0.05). The above mentioned changes may be responsible for insufficient functional recovery after lacunar strokes in abdominally obese patients.
    Tags lacunar strokes, abdominally obese, inflammation
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    Publication of the article «World of Medicine and Biology» №4(35), 2012 year, 010-013 pages, index UDK 616.831-005.1-056.5