Skrypnyk V. M., Avetikov D. S., Yеroshenko G. A.

MORPHOFUNCTIONAL JUSTIFICATION THE PREVENTION OF POSTOPERATIVE PATHOLOGIC SCARRING OF THE FACE AND NECK

---

About the author:	Skrypnyk V. M., Avetikov D. S., Yеroshenko G. A.
Heading	EXPERIMENTAL MEDICINE
Type of article	Научная статья
Annotation	Development and perfecting of methods of prevention of pathological seams of skin, is an actual task. Effectiveness of existing methods of prevention of seams remains poor. To prevention applied solution of "Lipin" and cream to "Dermofibraz" in the patient with the revealed polymorphism of a gene of elastin g28197 and research biopsy, histologic and immunohistochemical (definition of localization of cages positive to CD 2, CD 3, CD 4, CD 20, CD38. CD 68, Ki67) during prevention every 3 month. In 9 months of supervision the skin structure in situ transactions corresponded developed normotrofichesky a hem that confirmed histochemical researches. Considering above-mentioned expedient there would be cream use to "Dermofibraz" and than the liposomalny preparation "Lipin" for the purpose of prophylaxis of pathological scarring is more narrow at early stages of an adhesion of postoperative wounds.
Tags	postoperative scar, abnormal scar, prevention, microcirculation
Bibliography	Alster T.S., Tanzi E.L. Hypertrophic scars and keloids; etiology and management // Am. J. Clin. Dermatol. – 2003/ - №4.- P. 235 – 243 Atiyeh B. S. Nonsurgical management of hypertrophic scars: evidence-based therapies, standard practices, and emerging methods / B. S. Atiyeh.// Aesthetic Plast. Surg 2007.-Vol.31, № 5.-P. 468-492. Boutli-Kasapidou R Hypertrophic and keloidal scars: an approach to poly-therapy // R Boutli-Kasapidou, A. Tsakiri, E. Anagnostou et al. // Int. J. Dermatol.- 2005.-Vol.44, № 4.-P. 324-327. Brudnik U. Therapeutic problems connected with keloid treatment-new treatment possibilities. [Article in Polish]. / U. Brudnik, M. Podolec-Rubis, A. Wojas-Pelc // Przegl Lek.- 2006.-Vol.63, № 9.-P. 803-806. Chen M. A. Scar management: prevention and treatment strategies / M. A. Chen, T. M. Davidson // Curr. Opin. Otolaryngol. Head Neck Surg 2005— Vol. 13, №4.-P. 242-247. Gilman Т.Н. Silicone sheet for treatment and prevention of hypertrophic scar: a new proposal for the mechanism of efficacy / Т.Н. Gilman //Wound Repair and Regeneration. - 2003. - 11(3). - P. 235-236.
Publication of the article	«World of Medicine and Biology» №4(35), 2012 year, 096-098 pages, index UDK 617.51/.53-003.9-084