English Українська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    Maystruk N.I.

    PECULARITIES OF MANOSOCONJUGATES BIOSYNTHESIS BY CELLS OF PANCREAS EPITHELIUM AND MESENCHYME GERMS IN HUMAN EMBRYOS OF DIFFERENT TYPES OF IMPLANTATION


    About the author: Maystruk N.I.
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation Have been studied 122 human embryos in the age from 21 day to 12 weeks of the intrauterus development, which includes stage X - XXIII and beginning of the fetal period by classification of Carnegie institute and 42 embryos of tubal development to 8 weeks of gestation. Mannosocojugates (receptors of lectin of lens culinaris) in pancreas during uterine implantation appear first for embryos in age 43 days (14 mm of length) on apical surface and cytolemma of epithelial cells. To the end of the second month of embryogenesis mannosocojugates saved at one level. During the third month of development (embryos 30-70 mm of length) glycopolymers accumulate. Differentiation of mesenchymal cells in young fibroblasts is accompanied complete reduction of receptors of lens culinaris lectin. During atypical implantation amount of receptors of lens culinaris lectin changes toward diminishing, that testifies to violation of cells receptor apparatus and processes of adhesion.
    Tags human early embryogenesis, uterine pregnancy, tubal pregnancy, lectins, organogenesis, pancreas
    Bibliography
    • Антонюк В. O. Лектини та їх сировинні джерела / В. О. Антонюк // – Львів., ПП „Кварт", 2005. – 458 с.
    • Волошин Н. А. Лектины животного и растительного происхождения: роль в процессах морфогенеза / Н. А. Волошин, Е. А. Григорьева // Теоретична медицина. Журн. АМН України. – 2005. – Т. 11, № 2. – С. 223-237.
    • Горальський Л.П. Основи гістологічної техніки і морфофункціональні методи досліджень у нормі та при патології / Л. П. Горальський, В.Т. Хомич, О. І. Кононський // – Житомир «Полісся», 2011. – 215 с.
    • Луцик А.Д. Лектины в гистохимии / А.Д. Луцик,  Е.С. Детюк, М. Д. Луцик // – Львов.: Вища школа, 1989. – 139 с.
    • Шаповалова Е. Ю. Перераспределение гликоконъюгатов в раннем гистогенезе мезенхимных закладок трахеи и легких у человека при маточной и трубной беременности / Е.Ю. Шаповалова, И.А. Демьяненко, Л.С. Георгиевская // Вісник морфологии. – 2006. – Т. 9, № 3. – С. 215-219.
    • Brysk M. M. Endogenous lectin from terminally differentiated epidermal cells / M.M. Brysk, S. Rajaraman, P. Penn // Differentiation. – 1986. – Vol.32, N3. – P.230-237.
    • Baruah S. Presentation of advanced tubal pregnancy / S. Baruah, P. Latthe, G.P. Downey // J Obstet Gynaecol. – 2003. – Vol. 23, N 4. – P. 435-436.
    • De Dios I. Heterogeneous distribution of plasma membrane glycoconjugates in pancreatic acinar cells / I. De Dios, A. Urunuela, S. Sevillano // Biochem. Biophys. Acta. – 2000. – Vol. 1509, N 1-2. – P. 292-298.
    • Eggens I. A role of carbohydrate – carbohydrate interaction in the process of specific cell recognition during embryogenesis and organogenesis. Apreliminary note / I. Eggens, B. Fenderson, T. Toyokumi // Bioch.-Bioph. Res. Comm. – 1989. – Vol.158, N3. – P.913-920.
    • Garrone C. M. Tubaric pregnancy - an excellent idea? / C. M. Garrone,  P. R. Broso //  Med Hypotheses. – 2000. – Vol. 54, N 6. – P. 900-902.
    • Kelleher D. J. Large – scale isolation of dolichol – linked oligosaccharides with homogeneous oligosaccharides structures: determination of steady – state dolichol-linked oligosaccharides compositions / D. J. Kelleher, D. Karaoglu, R. Gilmore // Glycobiol. – 2001. – Vol.11, N4. – P.321-333.
    • Raedler A. Lectin – defined cell surface glycoconjugates of pancreatic cancer cells and their nonmalignant counterparts / A. Raedler, E. Schmiegel, R. Raedler // Expl. Cell Biol. – 1983. – Vol.51. – P. 19-28.
    • Shao R. Understanding the mechanisms of human tubal ectopic pregnancies: new evidence from knockout mouse model / R. Shao // Hum Reprod. – 2009. – Vol. 45, N 6. – P. 1265-1269.
    • Tezuca M. Differential analysis of the human anagen hair apparatus using lectin binding histochemistry / M. Tezuca, M. Ito, T. Tazava // Arch. Dermatol. Res. – 1991. – Vol.283, N3. – P.180-185.
    Publication of the article «World of Medicine and Biology» №4(41) 1 part 2013 year, 068-071 pages, index UDK 611. 013. 7/8 + 611 – 018 + 611.24 + 611.611