| About the author: |
Kasimov E. M., Aghayeva F. A., Kerimov M. I. |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
A retrospective analysis of 89 eyes of 72 patients that were injected with 4 mg/0,1 ml of IVTA for treatment of macular edema was performed. Observation period ranged from 3 to 30 months (mean observation period 12,02 ± 0,94 months).SOH was evaluated in 32 patients (39 eyes, 43.8 ± 5,26%). The mean level of IOP elevation was 10.9 ± 1,00 mmHg (5 - 27.3 mmHg). In 9 % cases high «steroid response» was revealed. However, in 9% of cases there is a pronounced "steroid response". 5 eyes (5,6%) with diabetic macular edema showed persistent ocular hypertension despite full glaucoma medications and required filtering surgery to control IOP. We have not found any reliable correlations between baseline IOP/related systemic diseases and IOP elevation after IVTA. İt is essential to be careful in recommendation of repeat İVTA injection to patients demonstrated SOH after first IVTA injection. |
| Tags |
intravitreal injection, ocular hypertension, secondary glaucoma, triamcinolone acetonide |
| Bibliography |
- Касимов Э. М. Стероидная офтальмогипертензия и глаукома/Э. М. Касимов, Ф. А. Агаева // Азербайджанский Медицинский Журнал. - 2013. – № 2.- C. 126-130.
- Armaly M. F. Statistical attributes of the steroid hypertensive response in the clinically normal eye. The demonstration of three levels of response / M. F. Armaly // Invest. Ophthalmol. – 1965. –Vol. 4. P. 187.
- Alldredge C. D. Intravitreal triamcinolone for the treatment of idiopathic juxtafoveal telangiectasis./ C. D.Alldredge, B. R.Garretson // Retina. – 2003. – Vol. 23.- P. 113–16.
- Beer P. M. Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single injection./ P. M. Beer, S. J. Bakri, R. J Singh // Ophthalmology. – 2003. – Vol. 110.- P. 681-6.
- Chen W.L. Argon laser trabeculoplasty for late glaucoma after intravitreal triamcinolone./ W.L.Chen, Y.Y.Tsai, C.C.Chiang, J.M.Lin // Acta Ophthalmol. – 2009. – Vol. 87, N 2. – P. 238-9.
- Chuang L. H. Secondary ocular hypertension after intravitreal injection with 2 mg or 4 mg of triamcinolone in retinal vein occlusion./ L. H. Chuang, L. Yeung, N. K. Wang [et al.] // J. Ocul. Pharmacol. Ther. – 2010. – Vol. 26, N 4. P. 325–328.
- Dong Z. Efficacy and complications of intravitreal injection of triamcinolone acetonide for refractory cystoid macular edema associated with- intraocular inflammation./ Z. Dong, K .Namba, N. Kitaichi // Jpn. J. 62. Ophthalmol. - 2008. - Vol. 52. - P. 374-379.
- Hollands H. A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes./ H. Hollands, G. Seif, S. Hollands [et al.] // Can. J. Ophthalmol. – 2010. – Vol. 45, N 5. – P. 484-488.
- Jonas J. B. Regression of neovascular iris vessels by intravitreal injection of crystalline cortisone./ J. B. Jonas, J. K. Hayler, A. Sofker // J. Glaucoma. – 2001. – Vol. 10. - P. 284–287.
- Jonas J.B. Intraocular pressure after intravitreal injection of triamcinolone acetonide./ J.B.Jonas, I.Kreissig, R. Degenring // Br. J. Ophthalmol. – 2003. – Vol. 87. – P. 24–7.
- Krishnan R. Viscocanalostomy for refractory glaucoma secondary to intravitreal triamcinolone acetonide injection./ R. Krishnan, N. Kumar, P. K. Wishart // Arch. Ophthalmol. – 2007.- Vol. 125, N 9. - P. 284-286.
- Park H. Y. Intraocular pressure elevation after intravitreal triamcinolone acetonide injection./ H. Y.Park, Yi K., H. K. Kim // Korean J. Ophthalmol. – 2005. – Vol. 19, N 2. - P. 122-127.
- Parke D. W. Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification / D. W.Parke, R. A. Sisk, S. K. Houston [et al.] // Clinical Ophthalmology. - 2012. Vol. 6. – P. 925–931.
- Quiram P. A. Severe steroid-induced glaucoma following intravitreal injection of triamcinolone acetonide / P. A. Quiram, C. R. Gonzales, S. D. Schwartz // Am. J. Ophthalmol. – 2006. – Vol. 141, N 3. - P. 580-582.
- Rhee D. J. Intraocular pressure alterations following intravitreal triamcinolone acetonide./ D. J. Rhee, R. E. Peck, J. Belmont [et al.] // Br. J. Ophthalmol. – 2006. – Vol. 90, N 8. – P. 999-1003.
- Razeghinejad M. R. Steroid-induced iatrogenic glaucoma./ M. R. Razeghinejad, L. J. Katz // Ophthalmic Res. -2012. - Vol. 47, N 2. – P. 66-80.
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| Publication of the article |
«World of Medicine and Biology» №3(45), 2014 year, 058-062 pages, index UDK 617.7-007.681:615 |
