| About the author: |
Partshaladze V. I., Goncharova O. A., Ilina I. M. |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
Based on the study of autoantibodies to GAD and ICA in 126 patients with an initial diagnosis of type 2 diabetes LADA set to 16.7%, with almost the same frequency in the subgroups with normal, overweight and obese. In patients with normal body weight in the absence of significant differences in age at the time of the debut of diabetes and duration of the disease was characterized by LADA trend towards greater frequency of hypertension and type 2 diabetes - a frequent pronounced increase in waist circumference and hypertriglyceridemia, which may indicate the heterogeneity of their cardiac risk. |
| Tags |
type 2 diabetes, cardiac risk factors |
| Bibliography |
- Атраментова Л. О. Статистичні методи в біології / Л. О. Атраментова, О. М. Утєвська // – Х.: ХНУ імені В.Н. Каразіна, - 2007. – 288 с.
- Кононенко И. В. Функциональное состояние β-клеток, иммунологические и клинико-биохимические характеристики у больных с медленно прогрессирующим аутоиммунным диабетом взрослых / И. В. Кононенко, С. А. Прокофьев, О. М. Смирнова // Проблемы эндокринологии. – 2004. – Т 50. - №1. – С. 18-22.
- Brahmkshatriya P. P. Characteristics and Prevalence of Latent Autoimmune Diabetesin Adults (LADA) / P. P. Brahmkshatriya, A. A. Mehta, B. D. Saboo [et al.] // ISRN Pharmacology. – 2012. – Vol. 2 – P. 3-11.
- Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications // Report of a WHO Consultation. – Geneva, - 1999.
- Doehner W. Inverse relation of body weight and weight change with mortality and morbidity in patients with type 2 diabetes and cardiovascular co-morbidity: An analysis of the PROactive study population / W. Doehner, E. Erdmann, R. Cairns [et al.] // Int J Cardiol. - 2011. - Vol. 162(1). – Р.20-26.
- Romero-Corral A. Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality / A. Romero-Corral, V. K. Somers, J. Sierra-Johnson [et al.] // Eur Heart J. – 2010. – Vol. 31 (6). – P.737-746.
- Naik R. G. Latent autoimmune diabetes in adults / R. G. Naik, B. M. Brooks-Worrell, P. Palmer // J. Clin. Endocrinol Metab. – 2009. – Vol.94 (12). – P. 4635-4644.
- Subedi B. H. Роль статинов в лечении сахарного диабета / B. H. Subedi, R. Tota-Mahara,i M. G. Silverman [et al.] //Практична ангіологіяю – 2014. - №2 (65). – С.28-34.
- Wildman R. P. The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004) / R. P. Wildman, P. Muntner, K. Reynolds [et al.] // Arch Intern Med. – 2008. – Vol.168(15). – P. 1617-1624.
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| Publication of the article |
«World of Medicine and Biology» №3(45), 2014 year, 080-083 pages, index UDK 616.379-008.64 |
