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    Stupnytska G. Y.

    ROLE OF ADYPOKINES IN THE PATHOGENESIS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE DEPENDING ON NUTRITIONAL STATUS


    About the author: Stupnytska G. Y.
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The study involved 45 patients with chronic obstructive pulmonary disease (COPD) and 15 individuals with normal lung function. Found that in COPD patients with obesity leptin level was higher. The serum content of resistin increased in comparison with the group of healthy individuals by 60% (p <0.01) - in patients with obesity at 72.4% (p <0.01) - in patients with a normal body mass index, 86% - in patients with overweight and 2.8 times (p <0.001) - in patients with obesity. The highest level of adiponectin and zinc-α2-glycoprotein installed in COPD patients with underweight. Imbalance of adypokines, the severity of which depends on the patient's nutritional status, is one of the important in pathogenesis of COPD.
    Tags chronic obstructive pulmonary disease, adypokines, nutritional status
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    Publication of the article «World of Medicine and Biology» №4(47) 2 part 2014 year, 063-066 pages, index UDK 616.24-007.272-008.9:612.397.2