About the author: |
Fedorov S. V. |
Heading |
CLINICAL MEDICINE |
Type of article |
Scentific article |
Annotation |
Syndrome of endogenous intoxication is available at heart failure (HF), and caused of poor prognosis and patient’s condition. In 357 patients with ischemic HF the dynamics of endogenous intoxication was detected by sorption ability of erythrocytes test (SAE). In basic treatment group this parameter decreased for 8,4%; in group with additional usage of ivabradine – for 5,4%, in group with additional prescription of ω-3 PUFA – for 8,4%; in group with their combination – for 11,2%. We didn’t observe of SAE values normalization in all groups. Thus, the strongest effect for endogenous intoxication was during additional usage of ω-3 PUFA. |
Tags |
heart failure, ivabradine, ω-3 PUFA, endogenous intoxication |
Bibliography |
- Ivanyuta L.I. Endogenna intoksikatsiya: prychyny vynyknennya, znachennya dlya klinichnogo zastosuvannya /L.I. Ivanyuta, I.O. Baranetska //Zdorovye zhenschiny. -2006. -No1. –S.252-256.
- Patogenez hronicheskoy serdechnoy nedostatochnosti: izmenenie deystvuyuschey paradigmy /V.V. Kalyuzhin, A.T. Teplyakov, Yu.Yu. Vecherskiy [i dr.] //Byulleten sibirskoy meditsiny. -2007. -No4. –S.71-80.
- Radchenko O.M. Sindrom endogennoyi intoksikatsiyi v klinitsi vnutrishnih hvorob (oglyad literatury ta vlasni sposterezhennya) / O.M. Radchenko, M.O. Kondratyuk // Medychna gidrologiya ta reabilitatsiya. — 2009. — T. 7, No 3. — S. 25-32
- Togaybaev A.A. Sposob diagnostiki endogennoy intoksikatsii / A.A. Togaybaev, A.V. Kurguzkin, I.V. Rikun, R.M. Karibzhanova // Lab. delo. –1988. -No9. –S.22-24.
- ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 /J. McMurrey, S. Adamopoulus, S. Anker [et al.] // European Heart Journal. – 2012. –Vol. 33. –P.1787–1847.
- Force T.L. Heart failure: molecules, mechanisms and therapeutic targets / T.L. Force // Circulation. -2007. -Vol. 115. –P. e347-e356.
- Helwig B.G. Increased interleukin-6 receptor expression in the paraventricular nucleus of rats with heart failure / B.G. Helwig, T.I. Musch // Am. J. Physiol. Regulatory Integrative Comp. Physiol. -2007. -Vol. 292. -P. R1165—R1173.
- Role of bacterial endotoxin in chronic heart failure: the gut of the matter /B.M. Charalambous, R.C. Stephens, I.M. Feavers [et al.] //Shock. -2007. –Vol.28. –P.15-23.
- Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from recent clinical trials /A. Antonopoulus, M. Margaritis, C. Antoniades [et al.] //Curr. Pharm. Des. -2012. –Vol.18. –P.1519-1530.
|
Publication of the article |
«World of Medicine and Biology» №4(47) 2 part 2014 year, 066-069 pages, index UDK 616.12-008.46+615.036.8+615.224 |