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    Grigorieva E. A., Monina E. V.

    RATS’ FEATURES OF THE REACTIVITY OF THE SUBCHONDRAL BONE IN THE EARLY POSTNATAL PERIOD AFTER ADMINISTRATION OF HYDROCORTISONE TO PREGNANT


    About the author: Grigorieva E. A., Monina E. V.
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation The study found that in the subchondral bone and intact control animals marked predominance of the relative area occupied by intertrabecular lacunas. In rats after administration of hydrocortisone to pregnant found a significant increase of the relative area occupied by intertrabecular lacunas subchondral bone compared to intact and control from 14 to 90 days of life.
    Tags subchondral bone, osteoarthritis, intertrabecular lacunas, bone trabeculae
    Bibliography
    • Grigoreva E. A. Metodicheskie osobennosti izucheniya stroeniya sustavnogo hryascha krys v rannem postnatalnom periode ontogeneza / E. A. Grigoreva // Problemy, dostizheniya i perspektivyi razvitiya mediko-biologicheskih nauk i prakticheskogo zdravoohraneniya- 2006. - T. 142, No 1. - S. 13-15.
    • Nasonov E. L. Glyukokortikoidyi v revmatologii (sistemnaya i lokalnaya terapiya) / E.L. Nasonov, N. V. Chichasova, V. Yu. Kovalev // – M.: - 1998, 160 s.
    • Anthony E. Potential significance of physiological and pharmacological glucocorticoids in early pregnancy / E. Anthony, T. Aris, Michael1 Papageorghiou // Human Reproduction Update, Vol.14, No.5 – 2008, P. 497–517,
    • Bellido M. Improving subchondral bone integrity reduces progression of cartilage damage in experimental osteoarthritis preceded by osteoporosis / M. Bellido, L. Lugo, J. A. Roman-Blas [et al.] // Cartilage Volume 19, Issue 10, October – 2011, P. 1228–1236.
    • Cleare A. J. Low-dose hydrocortisone in chronic fatigue syndrome: a randomised crossover trial. / E. Heap, G.S. Malhi, S. Wessely [et al.] // Lancet.- 1999 Feb 6, Vol.353(9151): P.455-458.
    • Christopher B. Post-traumatic osteoarthritis: from mouse models to clinical trials. / B. Christopher// Nature Reviews Rheumatology 9, August -2013, P.485-497.
    • Dodic M. Altered cardiovascular haemodynamics and baroreceptor-heartrate reflex in adult sheep after prenatal exposure todexamethasone / A. Peers, J. P. Coghlan, C. N. May [et al.] // Clinical Science – 1999, Vol. 97, P. 103-109.
    • Dodic M. Trends in Endocrinology and Metabolism / M.  Dodic // Arianne Peers, John P. Coghlan, Marelyn Wintour - 1999, Vol. 10, P. 86-91.
    • Grossman J. M. American College of Rheumatology 2010 Recommendations for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis / J.M. Grossman, R. Gordon, V.K. Ranganath [et al.] // Arthritis Care & Research Vol. 62, No. 11, November - 2010, P. 1515–1526.
    • Sonja B. Prenatal glucocorticoid exposure alters hypothalamic–pituitary–adrenal function and blood pressure in mature male guinea pigs/   Amita KapoorStephen G Matthews // J Physiol. Jul 1, - 2004; Vol. 558(Pt 1): P. 305–318.
    • Tadashi H. The Role of Subchondral Bone Remodeling in Osteoarthritis Maureen Pickarski / H. Tadashi // Duong ARTHRITIS & RHEUMATISM Vol. 50, No. 4, April - 2004, P. 1193–1206.
    Publication of the article «World of Medicine and Biology» №4(47) 2 part 2014 year, 104-107 pages, index UDK 611.71:57.08