| About the author: |
Nefodova O. O. |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The aim of the experiment was to determine the morphogenetic patterns cardiogenesis influenced by lead acetate in isolated input and combined administration of citrate silver. Research materials were chosen as experimental animals rats. All rats were divided into 3 groups: Group 1 - animals injected solution of lead acetate at a dose of 0.05 mg / kg; Group 2 - animals injected solution of lead acetate at a dose of 0.05 mg / kg and a solution of silver citrate in a dose 2mkh / kg; Group 3 - control. Analysis of the results showed a negative effect of lead acetate on the course of cardiogenesis, which consisted of thinning of the interventricular septum wall, reducing the thickness of the ventricle due to thinning of the compact layer and reducing the weight of the heart. The combined influence of lead acetate and silver citrate, an increase in heart weight and restore thickness of the interventricular septum, which testifies to the compensatory action of silver citrate toxicity of lead acetate. The results of the experiment show that silver citrate obtained by aquananotechnology can be considered as a new bioantohonist of lead acetate in influencing to cardiogenesis in rats. |
| Tags |
embryogenesis, cardiogenesis, lead acetate, gold citrate, heart, myocardium |
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| Publication of the article |
«World of Medicine and Biology» №4(47) 2 part 2014 year, 169-172 pages, index UDK 611.12-034:591.33-092.9 |
