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    Shkumat M., Leonov Y., Pishel I.

    EFFECT OF IGF-1 ON WOUND HEALING IN AGED FVB MICE WITH K14SIGF1 TRANSGENES


    About the author: Shkumat M., Leonov Y., Pishel I.
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation One of the main factors that can exert influence on the state and the rate of skin regeneration is IGF-1. A morphological studies of wound healing rate was performed in wild-type and transgenic FVB-K14/mIGF-1 mice of different ages to determine the effect of IGF-1 on wound healing in aging. It has been shown that an increase in area and thickness of the regenerating epithelium in the wound of transgenic animals compared with wild-type.
    Tags skin, wound healing, aging, IGF-1
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    Publication of the article «World of Medicine and Biology» №4(47) 2 part 2014 year, 210-213 pages, index UDK 612.79:612.67.014.3