| About the author: |
Savchenko I. M., Garbuzova V. Yu. |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
During the work, was used the venous blood of 108 women diagnosed with leiomyoma (average age was 47,82 ± 6,6 years) and the venous blood of women without it (average age was 69,75 ± 8,4 years). The С-1562Т detection of the MMP-9 gene polymorphism was conducted with the help of polymerase chain reaction method with further restriction fragments length analysis while allocating them by electrophoresis in agarose gel. Statistical data processing was carried out with the help of SPSS-17 software package. In addition, the differences were determined by χ² criterion. Values with Р<0,05 were accepted as accurate. Results. The received results show the absence of considerable differences in the distribution of genotypes by the polymorphism С-1562Т of the ММР-9 gene between patients diagnosed with leiomyoma and patients of the control group. |
| Tags |
matrix metaloproteіnaza–9, single nucleotide polymorphism, leiomyoma, COPD, gastritis |
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| Publication of the article |
«World of Medicine and Biology» №1(48), 2015 year, 072-077 pages, index UDK 618.14-006 |
