Pikul E V.

ATYPCAL INFECTION IN CHILDREN

---

About the author:	Pikul E V.
Heading	LITERATURE REVIEWS
Type of article	Review article
Annotation	In the thesе presents an analysis based literature data, the causes and clinical manifestations of the various forms of atypical infections in children. In a world infected with up to 1 billion. People and every year new patients for chlamydia record 4 million аnd 100000 children with symptomatic forms of the disease, 15% of stillbirths, perinatal mortality rate - 35%. Mycoplasmosis in 77,3% of cases seen with other infections - chlamydia, virus, etc. Legionellosis today called the disease of industrialization. Chlamydia - a gram-negative microorganisms grupa that take place between viruses and bacteria. Mycoplasma infection treat class Mollicules and also on the structure stands on the middle between viruses, bacteria and protozoa. These microorganisms have RNA and DNA. Legionella pneumophila - Gram-negative pathogen, which allocates endotoхin and eхotoхin. Bol is open 40 species of Legionella from them 22 species include 35 serovars that are pathogenic to humans. In particular, the author paid much attention chlamydiоsis, mycoplasmosis and legionellosis as one of the atypical manifestations of infection in childhood. The pathogenesis of Chlamydia are destroying epithelial host cells, the occurrence of hemodynamic disturbances and destruction of chlamydia in cells, L-transformation and persistence. Respiratory Chlamydia in infants under 6 months of often develops on the background or after suffering conjunctivitis. Typically no data on contact with SARS patients. Most often diagnosed pneumonia, accompanied by bronchial obstruction. The first signs after intrapartum infection may be from 5 days to several months. Late of disease caused by subclinical course and activation under the influence of various factors. Features pathogenesis: mycoplasmosis is damage epithelial cells of the respiratory tract, including the process involved alveoli, leading to interstitial pneumonia. In severe cases, possible hematogenous dissemination of drift to other organs and development clinics hepatitis, meningitis, nephritis. Features Legionellosis pathogenesis is destruction agent terminal bronchioles and alveoli. Pulmonary infiltrate consisting of leukocytes, fibrin, alveolar cells, then can cause infectious-toxic shock and destruction of others. There are three forms Legionellosis: pneumonic, fever Pontiac and fever Fort Bragg. The incubation period of 2-10 days. Respiratory form has the following clinical picture: acute onset of febrile, dry cough and chest pain, then turns into productive cough with bloody sputum. In the treatment of atypical infections as etiotropnoy therapy used macrolides.
Tags	children, atypical infection, treatment
Bibliography	Buz'ko D. A. Perebіg vrodzhenoї mіkoplazmoznoї іnfekcії u nedonoshenih novonarodzhenih //Materіali spіl'noї ukraїns'ko-pol's'koї naukovo-praktichnoї konferencії neonatologіv «Novі tehnologії nadannja medichnoї dopomogi novonarodzhenim» - Kiїv – 2000 – S. 21-22. Bogadel'nikov I. V. Spravochnik po infekcionnyh boleznjah u detej / I. V. Bogadel'nikov, A. V. Kubyshkina, M. V. Loboda // -K.: -Simferopol': - 2008 - 390 s. Bogadel'nikov I.V. Differencial'nyj diagnoz infekcionnyh boleznej u detej / I. V. Bogadel'nikov // – Simferopol'. - 2009. - 689s. Vozіanova Zh. І. Іnfekcіjnі ta parazitarnі hvorobi / Zh. І. Vozіanova // - K.: Zdorov'ja, - 2000. - T.1- 854 s. Granitov V. M. Hlamidiozy / V.M. Granitov // – M.: Medicinskaja kniga – 2000. – 192 s. Dzhon Dzh. Bartlett. Infekcii dyhatel'nyh putej / Dzhon Dzh. Bartlett / – Moskva. – 2000. – 192 s. Kramarev S.O. Іnfekcіjnі hvorobi u dіtej (klіnіchnі lekcії). / S.O. Kramarєv // – K.: Morіon. – 2006. – 479 s. Kazmirchuk V. E. Principy interpretacii dannyh immunogrammy v praktike klinicheskogo immunologa / V. E. Kazmirchuk, D. V. Mal'ceva // – K.: - 2007. – 24 s. Koval'chuk L.V. Immunologija: praktikum / L.V. Koval'chuk [i dr.] // – M.: GJeONTAR-media, - 2010. – 176 s. Lapovec' L .E. Vibranі lekcії z laboratornoї medicini. / L.Є. Lapovec', G.B. Lebed', O.O. Jastrems'ka [ta іn.] // L'vіv. – 2013. – 340 s. Traverse G. M. Dіagnostika ta lіkuvannja vnutrіshn'outrobnih іnfekcіj u novonarodzhenih / G. M. Traverse, S. M. Cvіrenko // – 2002. – Poltava: Verstka – 106 s. Gerald L. Mandell. Principles and practice of Infection diseases seventh editions / L. Gerald Mandell, John E. Bennett, Raphael Dolin // – Churchill. Livigstone. - 2010. – 4011 p.
Publication of the article	«World of Medicine and Biology» №1(48), 2015 year, 212-217 pages, index UDK 616-053.31/.71:616.98