| About the author: |
Gasyuk N. V. |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The article presents the results of molecular genetic study of the role of nuclear transcription factor NF-κB1 in the pathogenesis of generalized periodontitis. Distribution of polymorphic variants of the gene NF-κB1u patients with intact periodontal and genotype (Del/Del) is 5 (11%) with genotype (Del/Ins) 23 (51%) with genotype (Ins/Ins) 17 (38%). Patients with generalized periodontitis is population distribution of genotype (Del/Del) 9 people (16%) with genotype (Del/Ins) under 30 (55%) and (Ins/Ins) 16 (29%). It was found that genotype (Del/Del) is unchanged and the determining factor that causes the development of generalized periodontitis, clinical picture which meets the quickly progressing. |
| Tags |
generalized periodontitis, genotype polymorphism, the transcription factor |
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| Publication of the article |
«World of Medicine and Biology» №3(51) 1 part 2015 year, 028-031 pages, index UDK 616.316.–091.8–092 |
