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    Maksymyuk H. V., Vorobets Z. D., Maksymyuk V. M.

    IL-6 , IL -8, IL -10 LEVEL IN MEN SPERM

    About the author: Maksymyuk H. V., Vorobets Z. D., Maksymyuk V. M.
    Type of article Scentific article
    Annotation The research was conducted in order to identify relationship of concentration of inflammatory and anti-inflammatory cytokines to the quality parameters of sperm. The trend to a positive correlation between the concentrations of IL-6 and IL-10 (r = 0,45) and concentration of sperm was found; IL-8 (r = 0,52) to the viscosity of semen, IL-10 (r = 0,50) – to the number of motile cells. Trend to negative correlation between IL-6 (r = -0,42) and IL-8 (r = -0,55) with the number of live spermatozoa was present, but IL-10 (r = -0,70) was close to the volume of semen. Strong positive correlation between concentration parameters of cytokines was observed in groups of IL-8 and IL-6 (r = 0,74) and IL-10 and IL-6 (r = 0,72) in the researched semen ejaculates. The studies suggest that increased concentration of IL-6 and IL-8 results in decreasing semen quality. This might be related to the processes that lead to men infertility. The increased concentration of IL-10 in the ejaculates optimizes the parameters of spectrogram.
    Tags fertile and infertile men, IL-6, IL-8, IL-10
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    Publication of the article «World of Medicine and Biology» №3(51) 1 part 2015 year, 059-063 pages, index UDK 616.155.3-097.36:616.69-008.8-074