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    Maksymyuk H. V., Vorobets Z. D., Maksymyuk V. M.

    IL-6 , IL -8, IL -10 LEVEL IN MEN SPERM


    About the author: Maksymyuk H. V., Vorobets Z. D., Maksymyuk V. M.
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The research was conducted in order to identify relationship of concentration of inflammatory and anti-inflammatory cytokines to the quality parameters of sperm. The trend to a positive correlation between the concentrations of IL-6 and IL-10 (r = 0,45) and concentration of sperm was found; IL-8 (r = 0,52) to the viscosity of semen, IL-10 (r = 0,50) – to the number of motile cells. Trend to negative correlation between IL-6 (r = -0,42) and IL-8 (r = -0,55) with the number of live spermatozoa was present, but IL-10 (r = -0,70) was close to the volume of semen. Strong positive correlation between concentration parameters of cytokines was observed in groups of IL-8 and IL-6 (r = 0,74) and IL-10 and IL-6 (r = 0,72) in the researched semen ejaculates. The studies suggest that increased concentration of IL-6 and IL-8 results in decreasing semen quality. This might be related to the processes that lead to men infertility. The increased concentration of IL-10 in the ejaculates optimizes the parameters of spectrogram.
    Tags fertile and infertile men, IL-6, IL-8, IL-10
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    Publication of the article «World of Medicine and Biology» №3(51) 1 part 2015 year, 059-063 pages, index UDK 616.155.3-097.36:616.69-008.8-074