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    Fushtey I. M., Mochonyi V. A.

    FEATURES VASCULAR REMODELING AND MARKERS OF IMMUNE-INFLAMMATORY RESPONSE IN PATIENTS WITH EH STAGE II


    About the author: Fushtey I. M., Mochonyi V. A.
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation Clinical and pathogenetic significance of immuno-inflammatory response in the occurrence of coronary heart disease (CHD) in patients with essential hypertension (EH) is insufficiently studied. To determine the degree of vascular remodeling (MS) and its relationship with the concentration of immuno-inflammatory markers in blood plasma is a complex clinical and paraclinical study of 180 patients with essential hypertension (EH) II stage. Established that the velocity of the pulse wave (SHRPH) in aorto-femoral segment (ACC) was highest when combined CHD and GC (11,4 ± 0,5 m / s to 10,1 ± 0,2 m / s in patients with EH without CHD, p <0,05). Found a reliable direct communication medium strength (R = + 0,31, p = 0,0004) between the level of IL-1β and thickness of intima-media distal segment of the common carotid artery and between SHRPH by ACC and interleukin-1β ( R = + 0,23, p = 0,01).
    Tags hypertension, coronary heart disease, vascular remodeling, immuno-inflammatory markers
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    Publication of the article «World of Medicine and Biology» №4(53) 1 part 2015 year, 077-081 pages, index UDK 616.12-008.331.1+616.12-005.4]:611.018.74-07