About the author: |
Z. M. Nebesna |
Heading |
EXPERIMENTAL MEDICINE |
Type of article |
Scentific article |
Annotation |
Submicroscopic state of components of aero-hematic barrier of respiratory portion of lungs after thermal injury has been studied during the experiment, involving white rats, in condition of early necrectomy and application of ground substrate of freeze-dried xenograft and administration of surfactant agent. It has been found that the combined use of such correction agents prevents the development of lesions in the aero-hematic barrier structures and has positive effect on the progress of regenerative processes and their normalization at the late stages of the experiment. |
Tags |
aero-hematic barrier, ultrastructural changes, thermal injury, freeze-dried xenograft substrate |
Bibliography |
- Goral's'kij L. P. Osnovi gіstologіchnoї tehnіki і morfofunkcіonal'nі metodi doslіdzhen' u normі ta pri patologії / Goral's'kij L. P., Homich V. T., Konons'kij O. І. – Zhitomir: Polіssja, 2011. – 288 s.
- Ershov A. Povrezhdenie i zameshhenie surfaktanta pri respiratornom distress-sindrome vzroslyh / A. Ershov // Rezhim dostupu : http://www.critical.ru/actual/IT/surfactant.htm
- Nagajchuk V. І. Suchasnі pіdhodi do nadannja dopomogi hvorim z opіkami / V. І. Nagajchuk // Mistectvo lіkuvannja. – 2010. – № 5. – S. 24–27.
- Netjuhajlo L. G. Patogenez opіkovoї hvorobi (v 2 chastinah) / L. G. Netjuhajlo, S. V. Harchenko, A. G. Kostenko // Svіt medicini ta bіologії. – 2011. – № 1. – S. 127–131, 131–135.
- Novikov N. Ju. Patomorfologicheskie izmenenija aerogematicheskogo bar'era pri ostrom respiratornom distress-sindrome v jeksperimente / N. Ju. Novikov, L. V. Tyshkevich, K. N. Dzhansyz // Patologіja. – 2012. – № 1 (24). – S. 53–56.
- P’jatnic'kij O. Ju. Eksperimental'ne doslіdzhennja farmakologіchnih vlastivostej substratu krіokonservovanoї shkіri svinі / Ju. S. P’jatnic'kij, L. V. Jakovlєva, O. Ju. Koshova // Klіnіchna farmacіja. – 2013. – T. 17, № 1. – S. 56–62.
- Cimbaljuk A. V. Vikoristannja podrіbnenogo substratu lіofіlіzovanogo ksenodermoіmplantata dlja mіscevogo lіkuvannja opіkovih hvorih z іnfіkovanimi ranami ІІІ-ІV stupenіv / A. V. Cimbaljuk, N. V. Guda, O. O. Kirik // Shpital'na hіrurgіja. – 2013. – № 1. – S. 81–84.
- Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type II cells / N. Dreyer, S. Mühlfeld, A. Fehrenbach // Respiratory Research. – 2008. – V. 9 (1) : 5. – Rezhim dostupu do zhurn. : http://respiratory-research.com/content/9/1/5
- Lachmann B. Surfactant Replacement Therapy: in Neonatal and Adult Respiratory Distress Syndrome / B. Lachmann. – Berlin : Springer–Verlag, 2012. – 378 p.
- Lepekha L. N. In vitro effects of pulmonary surfactant on macrophage morphology and function / L. N. Lepekha, E. A. Alexandrova, M. V. Erokhina // Bulletin of Experimental Biology and Medicine. – 2012. – V. 152. – P. 489–493.
- Vtiurin B. V. The comparative characteristics of pulmonary and renal ultrastructural changes in burn sepsis / B. V. Vtiurin, I. A. Chekmareva, E. N. Gordienko [et al.] // Arh. Patol. – 2008. – Vol. 70, N 1. – P. 29–35.
|
Publication of the article |
«World of Medicine and Biology» №4(54) 2 part 2015 year, 127-130 pages, index UDK 616-24-008.7-091.8-02:616-001.17-085.324:591.477:599.731.1]-092.9 |