EnglishУкраїнська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    Chernyavskaya E.A., Nevzorov V.P., Babiychuk V.G., Martynova Yu.V., Kulik V.V.

    ULTRASTRUCTURE OF MYOCARDIAL BLOOD CAPILLARY ENDOTHELIAL CELLS IN YOUNG RATS WITH ALIMENTARY OBESITY ON BACKGROUND OF APPLYING THE CRYOPRESERVED CORD BLOOD PREPARATION


    About the author: Chernyavskaya E.A., Nevzorov V.P., Babiychuk V.G., Martynova Yu.V., Kulik V.V.
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation In the electron microscopic study of myocardium blood capillary endotheliocytes of rats with alimentary obesity on the background of introduced cryopreserved preparation of cord blood nucleated cells it has been shown that young experimental animals with simulated alimentary obesity, compared with intact control, there are developed the marked dystrophic and destructive disorders in submicroscopic architecture of endothelial cells. In more distant periods of the experiments in endothelial cells the reparative changes of organelles continued to develop and the activity of intracellular metabolic processes increased. The experimental data obtained in future will provide an opportunity to compare the dynamics of ultrastructural rearrangements of myocardium blood capillary endothelial cells of young and aged rats with obesity after application of cord blood nucleated cells.
    Tags alimentary obesity, cord blood nucleated cells, endothelial cells, mitochondria, rats
    Bibliography
    • Anisimova E.V. Patologiya organov pischevareniya pri ozhirenii (obzor literaturyi)/ E.V. Anisimova, I.V. Kozlova, S.V. Volkov [i dr.] // Saratovskiy nauchno-meditsinskiy zhurnal.-2011.-T.7,No.4.-S. 851-856.
    • Baranov V.G. Chuvstvitelnost k insulinu, tolerantnost k glyukoze i insulinovaya aktivnost krovi u kryis s alimentarnyim ozhireniem / V.G. Baranov, N.F. Baranov, M.F. Belovintseva // Problemyi endokrinologii.- 1972.-T. 6.-S. 52-58.
    • Babiychuk L.V. Dinamika ultrastrukturnyih perestroek kardiomiotsitov miokarda molodyih kryis v protsesse razvitiya i progressirovaniya nevrogennoy arterialnoy gipertenzii / L.V. Babiychuk, V.P. Nevzorov, O.F. Nevzorova [i dr.] // Harkivska hirurgichna shkola.-2012.-No.5(56).- S.24-29.
    • Yevdokimova T.A., Nikitina E.A. Rol fizicheskih nagruzok v profilaktike i lechenii ozhireniya (obzor literaturyi) / T.A. Yevdokimova, E.A. Nikitina // Sportivna meditsina.-2005.-No.1.-S. 79-86.
    • Kondakov I.K. K probleme patogeneza metabolicheskogo sindroma. Zhirovaya tkan i markeryi ostroy fazyi vospaleniya / I.K. Kondakov, S.N. Koval, I.A. Snegurskaya [ i dr.] // Arterialnaya gipertenziya.-2009.-No.3(5).-S.39-43.
    • Korzh A. N. Sovremennyie podhodyi k profilaktike ozhireniya / A. N. Korzh// Mezhdunarodnyiy meditsinskiy zhurnal.-2012.-No.3.-S. 39-43.
    • Pinhasov B.B. Metabolicheskiy sindrom u zhenschin s raznyimi tipami ozhireniya / B.B. Pinhasov, V.G. Selyatitskaya, I.V. Obuhov // Vestnik NGU.-2011.-T.9,No.2.-S.36-43.
    • Diamant M. Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus/ M. Diamant, H. J. Lamb, Y. Groeneveld [et al.] // Journal of the American College of Cardiology .-2003.-Vol.42,№2.-Р. 328–335.
    • Greenberg A., Obin M. Obesity and the role of adipose tissue in inflammation and metabolism/ A. Greenberg, M. Obin// American Journal of Clinical Nutrition.-2006.-№83.-Р. 461-465.
    • Roccanova L. The role of stem cells in the evolution of longevity and its application to tissue therapy/ L.Roccanova, P. Ramphal // Tissue Cell.- 2003.- Vol 35, № 1.- P. 79-81.
    Publication of the article «World of Medicine and Biology» №1(55), 2016 year, 169-174 pages, index UDK 616.127-056.52-092.4:612.649.011.87:615.014.41