| About the author: |
Alirzayeva F. V. |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
112 patients with allergic diseases have been examined. The patients were divided into 2 groups: I group (main) - 58 (adults - 18, children - 40) patients suffering from allergic diseases and dysbiosis, II group (comparison) - 34 (adults-12, children - 22) patients with allergic disease, without goiter. The increase in the mean level of IL-6 in adult patients with allergies and dysbiosis secondary to 2.9 times and 1.1 times in comparison with control and group II respectively was noted. The content of IL-1 in the blood in adults with allergies and dysbiosis was exceeded one adult from the control group - in 4,1 times and group II - 1.0. The content of TNF-α was lower in children with urticaria. A significant decrease in the concentration of TNF-α in the serum of children with decompensated stage. Therefore, a combined damage of allergic inflammation and dysbiosis was accompanied by more impaired cytokine network in serum. |
| Tags |
dysbacteriosis, Allergy, interleukins, children, adults |
| Bibliography |
- Allahverdieva L.I. Respiratornaya allergiya u detey / L.I. Allahverdieva, A. A. Eyubova // - Baku: Indigo, - 2008, 327 s.
- Guschin I.S. Ustranenie neizbezhnosti allergicheskogo otveta / I.S. Guschin // Pulmonologiya, - 2010, No.4, S. 23-33.
- Minushkin O.N. Fruktooligo – i fruktopolisaharidyi v korrektsii i profilaktike narusheniy mikrobiotsenoza kishechnika u bolnyih bronholegochnoy patologii, poluchayuschih antibakterialnuyu terapiyu / O.N. Minushkin, M.D. Ardatskaya, I.Yu. Chicherin // Eksp. i klin. gastroenterol., - 2011, No.3, S. 79-87.
- Yakovleva V. K. Vliyanie lecheniya parazitozov i disbakterioza kishechnika na techenie bronhialnoy astmyi / V.K. Yakovleva, G.B. Fedoseev, M.V. Eliseeva [i dr.] // Rossiyskiy allergologicheskiy zhurnal, Moskva: Farmarus Print Media, - 2011, No.5, S.16-20.
- Rebrova O.Yu. Statisticheskiy analiz meditsinskih dannyih. Primenenie paketa prikladnyih programm STATISTICA (3-e izdanie). / O.Yu. Rebrova // - Moskva: Media Sfera, - 2006, 305 s.
- Akdis M. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells / M. Akdis, J. Verhagen, A. Taylor [et al.] // J Exp Med., - 2004, Vol.199, P.1567–1575.
- Baena-Cagnani C.E. The international survey on the management of allergic rhinitis by physicians and patients (ISMAR) / C.E. Baena-Cagnani, G.W. Canonica, M.Z. Helal [et al.] // World Allergy Organization Journal,- 2015, Vol.8, P.10-20.
- Fiocchi A. World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Probiotics / A. Fiocchi, R. Pawankar, C. Cuello-Garcia [et al.] // World Allergy Organization Journal, 2015, vol.8, p.4-16.
- Hooper L.V. Immune adaptations that maintain homeostasis with the intestinal microbiota / L.V. Hooper, A.J. Macpherson // Nat Rev Immunol, - 2010, Vol.10, P.159-169.
- Lyons A. Bacterial strain-specific induction of Foxp3+ T regulatory cells is protective in murine allergy models / A. Lyons, D.O'Mahony, F.O'Brien [et al.] // Clin Exp Allergy, -2010, Vol.40, P.811-819.
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| Publication of the article |
«World of Medicine and Biology» №2(56), 2016 year, 009-013 pages, index UDK 616.-056.3-053.2:616-008.8 |
