Nazarchuk G.G.

MODERN ANTIMICROBIAL MATERIALS WITH PROLONGED MEDICATIVE QUALITIES IN OPHTHALMOLOGY

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About the author:	Nazarchuk G.G.
Heading	EXPERIMENTAL MEDICINE
Type of article	Scentific article
Annotation	Antiseptic properties of nylon, impregnated with antimicrobial composition, its clinical effectiveness in infectious complications’ prevention were evaluated. We found, that in 360 hours of decamehtoxin desorbtion from the nylon’s (9/0) surfase there is 1,491 mkg/mm2 decamehtoxin in the solution. According to the results of the research, advantages of the antimicrobial nylon 9/0 in infected perforating corneoscleral wounds were found: the colonisation level and frequency of post operation purulent-inflammatory complications were lower in comparison with the usage of traditional nylon (р<0,001). The data of our study show that antimicrobial nylon 6/0 in the infected eyelids’ wounds effectively stopped microbial colonization in comparison with the usage of traditional nylon (р<0,001). Suture material serves as double depo for decamehtoxin. Antimicrobial nylon 9/0 was proved to create effective local antimicrobial regime, which prevents post operation purulent-inflammatory complications of infected corneoscleral wounds. Postoperative period of infected eyelid wounds adapted with antimicrobial nylon doesn’t characterise with chronic inflammatory process in comparison with the usage of traditional nylon. The data of the research prove perspectives of the new antimicrobial composition’s usage for the impregnation of suture materials for ophthalmosurgery.
Tags	suture material, nylon, decamehtoxin, corneoscleral wound, eyelid wound, S. aureus
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Publication of the article	«World of Medicine and Biology» №2(56), 2016 year, 132-136 pages, index UDK 615.47.014.47:617.7