| About the author: |
Sokolik V. V. |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
In 46 patients with cognitive decline and dementia were studied biochemical markers of vascular disease (ACE), endothelial dysfunction (eNOS, ET1), chronic inflammation (Аβ40, Аβ42), neurodegeneration (NSE) and using correlation and analysis of variance set their priority due to age or degree of cognitive deficit. It was shown that the intensity of vascular disease and its contribution to cognitive decline and dementia formation can be seen in such biochemical markers as the angiotensin-converting activity (ACE) and β-amyloid peptide 42, whereas dynamic of eNOS, ET1 and β-amyloid peptide 40 serum levels are primarily due to age-related changes. |
| Tags |
age, dementia, NSE, АСЕ, еNOS, EТ1, Аβ40, Аβ42 |
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| Publication of the article |
«World of Medicine and Biology» №3(57), 2016 year, 062-068 pages, index UDK 616.8 |
